Archive

Left Inferior Pulmonary Vein Thrombosis and Secondary Lung Infarction Following Radiofrequency Catheter Ablation: A Diagnostic Challenge

Initial CT angiography read as isolated alveolar hemorrhage; repeat imaging at day 31 showed complete left inferior pulmonary vein thrombosis with secondary pulmonary infarction.

Cardiology · Cureus · 24 Sept

Clinical Performance and Safety of the Optima Non-compliant Percutaneous Transluminal Coronary Angioplasty Balloon in Contemporary Percutaneous Coronary Intervention: A Multicenter Real-World Study

Real-world multicentre data on a high-pressure NC balloon give you procedural success and short-term safety figures to weigh when choosing lesion preparation and stent optimisation devices.

Cardiology · Cureus · 24 Sept

First Presentation With Impending Cardiac Tamponade Leading to a New Diagnosis of Mediastinal Lymphoma: A Shared Learning Case on the Atypical Presentation of Pericardial Effusion and Cardiac Tamponade

A young woman with dyspnoea and oedema but no full Beck's triad had tamponade from undiagnosed mediastinal lymphoma; keep effusion on the differential when the classic signs are absent.

Cardiology · Cureus · 24 Sept

Gut microbiome shifts in chronic systolic heart failure are associated with disease severity and clinical improvement.

Microbiome composition tracked HF severity and clinical improvement, hinting at gut-derived targets or markers, but this is early mechanistic work with no therapy ready for patients.

Cardiology · Nature cardiovascular research · 24 Sept

Clinical and Echocardiographic Characterization of Stage B Heart Failure in Asymptomatic Adults With Cardiovascular Risk Factors

Nearly all asymptomatic at-risk adults had echo abnormalities, so screening echocardiography in patients with hypertension or diabetes may catch pre-HF before symptoms.

Cardiology · Cureus · 23 Sept

Clinical and Biochemical Responses to SGLT2 (Sodium-Glucose Cotransporter-2) Inhibitors in Patients With Rheumatic Heart Disease and Heart Failure

Adds Indian data on SGLT2 inhibitors in rheumatic heart disease heart failure, a group usually excluded from the landmark trials you rely on.

Cardiology · Cureus · 23 Sept

Vascular aging as a driver of organ dysfunction and systemic aging.

No primary outcome or effect size reported. Authors argue endothelial and mural cells instruct organ function via angiocrine and paracrine signalling, making microvascular aging a driver rather than a bystander.

Cardiology · Nature cardiovascular research · 23 Sept

Graves’ Disease and the Heart: Severe Reversible Left Ventricular Systolic Dysfunction With Apical Thrombus in a Young Woman With Relapsed Thyrotoxicosis

In young thyrotoxic patients with unexplained LV dysfunction, consider Graves' cardiomyopathy with apical thrombus — antithyroid therapy plus anticoagulation can fully reverse it.

Cardiology · Cureus · 23 Sept

Kidney Outcomes in Structural Heart and Cardiac Surgical Trials: The Case for Longitudinal Endpoint Reporting

Cardiac trial reports you rely on often omit longitudinal kidney outcomes, so post-procedure renal risk in your valve and surgical patients stays under-recognised.

Cardiology · Cureus · 22 Sept

Occurrence of Heart Failure-Related Clinical Signs in a Japanese Convalescent Rehabilitation Ward: A Cross-Sectional Pilot Study

HF signs are common in rehab inpatients and often missed; screen for them before attributing breathlessness or fatigue to deconditioning.

Cardiology · Cureus · 22 Sept

Cordis’ sirolimus drug-coated balloon earns FDA approval as a breakthrough device

A sirolimus-coated balloon now offers an alternative to repeat stenting for coronary in-stent restenosis, though Indian access and cost remain uncertain.

Cardiology · Fierce Biotech · 22 Sept

Glycyrrhizin-Induced Pseudoaldosteronism Contributing to Decompensated Heart Failure With Preserved Ejection Fraction

Ask heart failure patients about licorice and kampo preparations; stopping the culprit corrects hypokalemia and hypertension without diuretic escalation.

Cardiology · Cureus · 22 Sept

Proteome-wide genetic analyses identify ASGR1 as a potential biomarker linking smoking with ischemic heart disease.

ASGR1 may be the mediator between smoking and coronary disease, hinting at a target for risk stratification in smokers beyond standard risk factors.

Cardiology · Nature cardiovascular research · 22 Sept

Bioadaptive spatiotemporal nanomedicine promotes metabolic recovery after myocardial infarction through NAD(+) and UCP2 regulation.

Preclinical only: staged NAD+ release restored mitochondrial metabolism and limited remodeling in mice, so watch for human dosing and delivery data before it touches post-MI care.

Cardiology · Nature cardiovascular research · 22 Sept

Peripheral arterial disease: adverse impacts, disparities in outcomes, and the path ahead.

PAD affects over 300 million people worldwide, causing chronic pain, functional limitation, amputation, myocardial infarction, stroke and death, with burden concentrated in underserved groups.

Cardiology · Lancet · 22 Sept

Current advancements in the care of peripheral arterial disease: modern approaches to medical, endovascular, and surgical treatment.

Amputation risk is low in asymptomatic PAD and intermittent claudication, with only a few progressing to chronic limb threatening ischaemia; supervised exercise improves walking capacity and avoids revascularisation risks

Cardiology · Lancet · 22 Sept

Early Post-transcatheter Aortic Valve Implantation (TAVI) Haemodynamics With SAPIEN Balloon-Expandable and Evolut Self-Expanding Valve Platforms: A Retrospective Single-Centre Cohort Study

Valve choice at TAVI affects early gradients, so knowing how SAPIEN and Evolut differ helps you anticipate haemodynamics and follow-up echo findings.

Cardiology · Cureus · 22 Sept

Late-Onset Prosthetic Valve Dysfunction Associated With Hypoattenuated Leaflet Thickening Detected After a New Heart Murmur: A Case Report

A new murmur after sutureless bioprosthetic AVR may signal HALT; consider CT to detect leaflet thickening before overt valve failure develops.

Cardiology · Cureus · 22 Sept

Enhancing Inpatient Echocardiogram Request Appropriateness and Timeliness Using British Society of Echocardiography Guidelines: A Quality Improvement Project

Appropriate requests rose from 82/100 (82%) to 90/100 (90%), an absolute change of 8 percentage points (95% CI −1.7 to +17.8; p=0.153). Completion within 24 hours changed from 77/100 (77%) to 79/100 (79%).

Cardiology · Cureus · 21 Sept

The Dangers of Chest Compression: A Case Report

Post-CPR sternal and rib fractures can seed infected parasternal collections; consider this in resuscitated patients with persistent chest pain or fever.

Cardiology · Cureus · 20 Sept

Myocarditis Revealing a Pathogenic Desmoplakin (DSP) Variant: Implications for Genetic Testing Pathways

In young myocarditis patients, especially with a family history, consider desmoplakin testing — a positive result reframes this as arrhythmogenic cardiomyopathy needing lifelong surveillance.

Cardiology · Cureus · 20 Sept

New Statin-Safety Reassurance: How Far Can It Extend to South Asian Patients?

Statin safety data from Western cohorts may not transfer to South Asian patients, whose differing pharmacokinetics could alter myopathy and intolerance risk at standard doses.

Cardiology · Cureus · 19 Sept

Minimally Invasive Coronary Artery Bypass Grafting for Predominantly Multivessel Coronary Artery Disease: Early Perioperative Outcomes of 149 Patients

Adds single-centre evidence that multivessel MICS-CABG avoids sternotomy with acceptable early outcomes, though results remain confined to high-volume specialised centres.

Cardiology · Cureus · 19 Sept

Unmasking Brugada Syndrome With Oral Propafenone in a Resource-Limited Setting: A Case Report

Oral propafenone can unmask type 1 Brugada patterns where IV ajmaline or flecainide is unavailable, letting you confirm the diagnosis before a fatal arrhythmia does.

Cardiology · Cureus · 18 Sept

Discordance Between Gated Single-Photon Emission Computed Tomography Myocardial Perfusion Imaging and Coronary Angiography in Dilated Cardiomyopathy

In DCM, SPECT-MPI and angiography can disagree on ischaemic versus non-ischaemic aetiology, so don't let a perfusion report alone decide whether a patient needs revascularisation workup.

Cardiology · Cureus · 18 Sept

Underestimation of Low-Density Lipoprotein Cholesterol (LDL-C) Using the Friedewald Equation at Higher Triglyceride Levels: Evidence From a Method-Comparison Study

Mean bias rose to +20.2 mg/dL (-17.0 to 57.5) at TG 250-300 and +26.5 mg/dL (-17.7 to 70.6) above 300 mg/dL; 58.7% and 58.1% respectively were assigned to a lower LDL-C band.

Cardiology · Cureus · 18 Sept

Cardiometabolic Risk Factors, Obesity Phenotypes, and Novel Anthropometric Indices in Patients With Acute Coronary Syndrome: A Hospital-Based Case-Control Study in Central India

BMI was not associated with ACS (Exp(B) 1.208, 95% CI 0.816-1.790, p=0.345). WHtR was (Exp(B) 2.473, 95% CI 1.638-3.732). MUO versus MHNW: OR 3.33, 95% CI 1.10-10.12.

Cardiology · Cureus · 17 Sept

Intravascular Ultrasound-Guided Iliofemoral Venous Stenting: In-Stent Mural Thrombus as a Possible Early Sign of Occult Malignancy

In-stent mural thrombus after iliofemoral venous stenting may signal undiagnosed cancer, so consider malignancy workup when it appears on surveillance imaging.

Cardiology · Cureus · 17 Sept

Oura, Counsel Health join CMS ACCESS model to test whether wearables and AI can improve chronic care at scale

If CMS pays for AI-guided remote monitoring in cardio-kidney-metabolic disease, your chronic-care workflow may shift to wearable-driven data between visits.

Cardiology · Fierce Healthcare · 17 Sept

Longeveron’s phase 2b stem cell flop spurs cost cutting, exploration of ‘all options’

A phase 2b mesenchymal stem cell trial in hypoplastic left heart syndrome missed its endpoint, so don't expect this cell therapy to reach your paediatric cardiac patients soon.

Cardiology · Fierce Biotech · 17 Sept

Tocilizumab in Acute Coronary Syndromes: A Systematic Review of Randomized Controlled Trials

Tocilizumab more than halved CRP area under the curve in three intravenous trials (all p < 0.001); one trial improved myocardial salvage index, but MACE and six-month clinical outcomes did not differ.

Cardiology · Cureus · 16 Sept

Minimally Invasive Coronary Artery Bypass Grafting (MICS-CABG) Versus Conventional Off-Pump Coronary Artery Bypass Grafting (OPCAB): A Single-Center Analysis of Early Outcomes and Institutional Experience

Ventilation was 8.80 ± 3.97 hours with MICS-CABG versus 4.22 ± 2.64 hours with OPCAB; chest drainage 887.0 ± 611.8 mL versus 328.9 ± 116.1 mL. No mortality or sternotomy conversion in either group.

Cardiology · Cureus · 16 Sept

Comparative Outcomes of Beta-Blockers vs Non-Dihydropyridine Calcium Channel Blockers in Heart Failure With Preserved Ejection Fraction: A Systematic Review and Meta-Analysis

In HFpEF, beta-blockers and non-dihydropyridine calcium channel blockers show comparable outcomes, so choice can hinge on heart rate, exercise tolerance and tolerability rather than assumed superiority.

Cardiology · Cureus · 16 Sept

Risk-guided cardioprotection in cardio-oncology.

Trials selecting patients by cancer type and treatment regimen show modest to no significant benefit on subclinical or clinical measures of cardiotoxicity; risk-guided selection is proposed but not yet tested

Cardiology · Nature cardiovascular research · 16 Sept

Beyond Prognosis: A Systematic Review of the Neutrophil-to-Lymphocyte Ratio as a Modifiable Cardiovascular Biomarker

IL-6 inhibition gave the clearest dose-dependent NLR reduction; glutathione, cardiac rehabilitation, time-restricted eating, curcumin and hyperoxia also looked favourable. SGLT2 inhibitor results were inconsistent. Clinical outcomes were rarely reported and underpowered.

Cardiology · Cureus · 15 Sept

Age-associated loss of lymphatic vessels promotes cardiac inflammation.

Aging lowered cardiac lymphatic density in humans and mice, with immune infiltration, fibrinogen and amyloid accumulation and myocardial edema; Vegfc overexpression or Il33 silencing restored lymphatic density and homeostasis in aged hearts.

Cardiology · Nature cardiovascular research · 15 Sept

A Synopsis of the 2025 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline for Lipid Management for Cardiovascular Disease Risk Reduction.

New: PREVENT calculator for primary prevention risk estimation; routine lipid monitoring no longer discouraged; coronary artery calcium for intermediate-to-high risk with uncertainty; one-time lipoprotein(a) testing; moderate-intensity statins for adults with HIV even at low 10-year risk.

Cardiology · Annals · 15 Sept

Renal Dysfunction and Cardiorenal Syndrome in Acute Heart Failure: A Systematic Review of Residual Congestion and Decongestion Response

Residual congestion was consistently associated with worse clinical outcomes, while worsening renal function during effective decongestion did not uniformly predict adverse renal or cardiovascular events.

Cardiology · Cureus · 14 Sept

Managing Cardiac Amyloidosis in a Rural Cardiology Practice: Bridging Gaps in Specialized Evaluation and Disease-Modifying Treatment

All three patients were effectively evaluated using a streamlined diagnostic pathway and started on disease-modifying therapy promptly, despite limited access to advanced imaging, biopsy and genetic testing

Cardiology · Cureus · 14 Sept

Ischemic Stroke During Rivaroxaban Therapy: The Importance of Food-Dependent Absorption and Careful Assessment Before Antithrombotic Escalation

Before adding an antiplatelet after a stroke on rivaroxaban, check food-dependent absorption and timing — escalation may raise bleeding without fixing the cause.

Cardiology · Cureus · 14 Sept