Archive

Establishing the Baseline: A Practical Approach to Admitting Adults With Intellectual Disability

No numerical results. The authors propose recording eight baseline domains at admission with someone who knows the patient, and treating any change from that baseline as possible acute illness.

General Medicine · Cureus · 21h

Comparative Efficacy, Safety, and Healthcare Resource Utilization of Levosalbutamol Versus Racemic Salbutamol in Asthma and Wheezing: A Systematic Review of Physiological, Clinical, and Management Outcomes

Levosalbutamol gives comparable bronchodilation with fewer tachycardia and tremor effects, so consider it when beta-agonist side effects limit dosing in asthma and wheezing.

General Medicine · Cureus · 1d

Prevalence of Anemia in Hospitalized Internal Medicine Patients: A Cross-Sectional Study

Anemia is common in your admitted medical patients; this gives prevalence and complication data to justify routine CBC review and transfusion thresholds on the ward.

General Medicine · Cureus · 1d

Improving Physician Orders for Life-Sustaining Treatment (POLST) Documentation Through an Age-Friendly Health Systems 4Ms What Matters Workflow in an Outpatient Geriatric Clinic

Embedding a POLST prompt in routine geriatric visits raised documented end-of-life preferences — a workflow you can copy into your own outpatient practice.

General Medicine · Cureus · 1d

Clinical Outcomes of Medication-Related Osteonecrosis of the Jaw After Switching From Antiresorptive Agents to Teriparatide

If your patient on bisphosphonates or denosumab develops exposed jaw bone, switching to teriparatide may be a treatment option worth discussing with their oral surgeon.

General Medicine · Cureus · 1d

Association Between Oral Hygiene and Bronchoscopic Microbiological Findings in Patients Undergoing Bronchoscopy for Non-infectious Indications

Higher oral hygiene score trended toward lower odds of oral flora (aOR 0.853 per point, 95% CI 0.707-1.028, p = 0.094). Yield differed by modality: BAL 86%, biopsy 43%, brushings 15%; BAL-brush concordance poor (κ = 0.042)

General Medicine · Cureus · 2d

Humana, athenahealth collaborate on expanded electronic prior authorizations nationwide

If your practice bills Humana through athenahealth, prior auth requests move into the EHR workflow, cutting phone and fax time before procedures and imaging.

General Medicine · Fierce Healthcare · 2d

Diabetes Risk and Depression Among Adults Without Known Diabetes: A Community-Based Mixed-Methods Study in Rural Puducherry, India

When you screen for diabetes risk in rural patients, treat depressive symptoms as part of the same picture rather than a separate referral.

General Medicine · Cureus · 2d

Comparative Effects of Cold and Warm Pelotherapy on Disease Activity and Function in Ankylosing Spondylitis: A Prospective Study

Both peloid temperatures improved disease activity and spinal function in AS, so you can offer balneotherapy as an adjunct without insisting on a specific temperature.

General Medicine · Cureus · 2d

Follow-Up Blood Cultures in Streptococcal and Enterococcal Bacteremia: A Systematic Review of Persistent Bacteremia and Its Clinical Significance

Repeat cultures after strep or enterococcal bacteremia are common but of uncertain yield; this review clarifies when persistence is likely enough to justify the extra draws.

General Medicine · Cureus · 2d

Dermoscopy in General Practice: A Retrospective Study of Skin Lesion Assessment, Diagnostic Yield, and Two-Week-Wait (2WW) Referrals

If GP dermoscopy sharpens triage, fewer benign lesions reach 2WW clinics and true melanomas get seen sooner — worth knowing before you adopt it.

General Medicine · Cureus · 2d

Measles is reemerging; most US physicians have never treated a case

Most of us have never managed measles; this review covers recognition, isolation and post-exposure prophylaxis before the next outbreak reaches your OPD.

General Medicine · Annals · 2d

Timing of Long COVID Improvement in Prospectively Followed RECOVER-Adult Participants.

Gives you real remission probabilities to quote when long COVID patients ask how long this lasts, rather than vague reassurance.

General Medicine · Annals · 2d

Generative Artificial Intelligence in Clinical Reasoning Education: A Focused Review and Framework

Most studies report associations or short-term improvement rather than AI-specific educational effects; several rely on satisfaction outcomes, pre-post designs or historical controls. Feasibility and selected short-term gains are supported, but durable learning is not established.

General Medicine · Cureus · 3d

Zocdoc opens infrastructure to AI agents, launches partnership with Instinct

If booking agents like Instinct fill your slots, your front desk workload and no-show patterns change; worth knowing how appointments reach you.

General Medicine · Fierce Healthcare · 3d

Reducing Short-Acting Beta-2 Agonist (SABA) Overuse in Asthma: A Quality Improvement Project in Primary Care

Patients issued two SABA inhalers fell 62.8% from 94 to 35; patients reporting at least one poor-control symptom fell 51.4% from 37 to 18. In cycle two, 18/23 (78.2%) contacted still reported poor control.

General Medicine · Cureus · 3d

Efficacy and Safety of Ritlecitinib in Severe Alopecia Areata: A Systematic Review

JAK3 inhibition is now a systemic option for totalis/universalis patients you currently have little to offer beyond steroids; know the response and adverse-event profile before prescribing.

General Medicine · Cureus · 3d

Disseminated Bullous Impetigo in an Immunocompetent Young Adult Following Travel to Costa Rica

Consider disseminated staphylococcal bullous impetigo in healthy adults with widespread bullae after minor abrasions, not just children, so you culture and treat rather than mislabel it.

General Medicine · Cureus · 3d

Povorcitinib for nonsegmental vitiligo: two randomized, controlled, phase 3 STOP-V trials.

An oral JAK1 inhibitor with 52-week phase 3 data would be the first systemic option for moderate-to-severe vitiligo, a condition you currently manage with topical steroids and off-label use.

General Medicine · Nature Medicine · 3d

Athenahealth launches tool to bring patient health records into Anthropic's Claude

Patients will soon query their own records through Claude and arrive with AI-generated interpretations; expect to correct summaries and clarify what the data does and doesn't mean.

General Medicine · Fierce Healthcare · 4d

Efficacy and Safety of Faropenem in Bangladeshi Adults With Community-Acquired Pneumonia: A Randomized Controlled Trial

Clinical cure at days 10-14 was 98.5% with faropenem versus 95.3% with comparator (risk difference +3.1%, 95% CI -2.8 to +9.1; relative risk 1.03, 95% CI 0.97-1.10). Adverse events 9.2% versus 12.5%; no serious adverse events, no withdrawals.

General Medicine · Cureus · 4d

Foodborne outbreak following a mass gathering in Karnataka, India: Epidemiological and environmental evidence implicating an uncooked food item.

Shigella spread via an uncooked item with a 34-hour incubation and 37% attack rate — ask about shared food exposure when diarrhoea clusters after local events.

General Medicine · Indian journal of medical research · 4d

Protein-based resistance in-silico model (PRISM-TB) for rapid prediction of drug-resistant tuberculosis using machine learning.

Random Forest correctly identified 351 of 374 WHO-graded resistant mutations (recall 0.939, accuracy 0.818); Extra Trees had F1-score 0.942, accuracy 0.941. Random Forest reached ROC-AUC 0.973 using only 10 features.

General Medicine · Indian journal of medical research · 4d

Digital reminder systems for improving adherence to anti-rabies vaccination among animal bite victims: A systematic review.

All three reported improved adherence. Vaccination completion was 70% vs 53% with telephonic reminders and 93% vs 78% with SMS. Tanzanian SMS adherence across four doses was 62%, 50%, 29%, 13% versus 48%, 41%, 22%, 7%.

General Medicine · Indian journal of medical research · 4d

From Pseudomembrane to Molecular Confirmation: A Laboratory-Confirmed Outbreak of Toxigenic Respiratory Diphtheria in Nagpur, India

Toxigenic diphtheria still clusters in under-vaccinated Indian communities — keep it on your differential for a grey pseudomembrane and check immunization status.

General Medicine · Cureus · 5d

Establishing Biological Reference Intervals From 2 Million Routine Hospital Laboratory Results of 59,141 Patients Using an Indirect Method: Evidence From Adult and Pediatric Moroccan Populations

Reference intervals were established for 26 analytes across age and sex groups, with 90% bootstrap confidence intervals. Transaminases, alkaline phosphatase, urea and creatinine agreed with existing intervals; sodium, calcium, albumin, glucose, HbA1c, uric acid, GGT and LDH limits shifted.

General Medicine · Cureus · 5d

Persistent Borrelia burgdorferi Peptidoglycan in Postinfectious Lyme Arthritis: Innate Immune Sensing and Translational Implications

No study has shown that persistent peptidoglycan or NOD2 signalling causes human postinfectious synovitis; human evidence is limited to peptidoglycan detection in synovial fluid from closely related research groups, not independently replicated.

General Medicine · Cureus · 5d

Comparison of Lyophilized and Dry Powder Colistin Formulations for Nebulized Treatment of Pneumonia Caused by Carbapenem-Resistant Gram-Negative Bacteria: A Retrospective Before-and-After Cohort Study

Day-14 favorable clinical response was 65.0% with lyophilized versus 63.3% with dry powder colistin (p=0.904). Day-7 response (90.0% vs 76.7%) and eradication (90.0% vs 66.7%) favoured lyophilized but were not statistically significant.

General Medicine · Cureus · 5d

Outcomes and Benefits of Using Twice Daily Nebulised Hypertonic Saline in T2-Low and T2-High Asthma With Bronchial Hypersecretion: A Retrospective Cohort Study

Mean exacerbations fell from 2.18 to 1.20 per year (p < 0.001) and mean hospital admissions from 0.43 to 0.15 (p=0.006); 44 of 48 tolerated treatment beyond one year

General Medicine · Cureus · 5d

Clinical Features, Treatment, and Outcomes of Sepsis by Culture Status in Hospitalized Adults: A Retrospective Cohort Study

Culture-negative sepsis is common in Indian hospitals; this cohort shows whether your culture-negative patients differ in treatment and mortality from culture-positive ones.

General Medicine · Cureus · 5d

Efficacy and Safety of Janus Kinase Inhibitors in Polymyalgia Rheumatica: A Systematic Review

If JAK inhibitors hold up, your steroid-dependent PMR patients may get a taper option that avoids years of cumulative glucocorticoid toxicity.

General Medicine · Cureus · 5d

Karnataka govt pauses circular on medicine price disclosure by hospitals

Itemised procurement-vs-MRP billing is on hold, so private hospitals in Karnataka face no immediate mandate to reveal medicine margins to patients.

General Medicine · ETHealthworld · 5d

Severe Encephalopathy Associated With Ivermectin Use and Extensive CYP3A4 Inhibition in a Patient Undergoing Self-Directed Treatment for Malignancy

Ask about unregulated self-medication in cancer patients on CYP3A4 inhibitors — this interaction produced severe encephalopathy at doses otherwise tolerated.

General Medicine · Cureus · 5d

Efficacy of High-Velocity Nasal Insufflation in the Treatment of Hypercapnic Respiratory Failure: A Systematic Review and Meta-Analysis

A nasal cannula option may spare hypercapnic patients the mask intolerance and pressure-related harms of NPPV, though randomized evidence remains thin.

General Medicine · Cureus · 5d

Charting a course to men's health and wellbeing: applying a lens of power and politics to improve men's health outcomes.

Men present late and die earlier; recognising gendered and structural barriers in your male patients can prompt earlier screening and referral.

General Medicine · Lancet · 5d

A global men's health epidemiology within an intersectional framework.

Men in marginalised groups carry the heaviest disability burden — screening and risk-factor work in these patients is where the gap is widest.

General Medicine · Lancet · 5d

FDA Approves First Plasmid DNA-based Immunotherapy for Adults with Recurrent Respiratory Papillomatosis

Adults with recurrent respiratory papillomatosis who face repeated debulking surgeries now have a first-in-class DNA immunotherapy option targeting HPV-driven disease.

General Medicine · FDA — Press Announcements · 6d

Who’s responsible when clinical AI goes wrong? AMA weighs in

If you use AI tools in practice, this framework sketches who owns a wrong output — you, the vendor, or the health system — before liability lands on you.

General Medicine · Fierce Healthcare · 6d

Weekly Rundown: Doximity launches DoseCheck; AI recommends costlier care than doctors, study finds

A study finding AI models recommend costlier care than doctors is a caution before you let triage or ordering tools shape decisions for your patients.

General Medicine · Fierce Healthcare · 6d

Erythromelalgia Unmasking a Triple-Negative Essential Thrombocytosis Phenotype After Recurrent Arterial Thrombosis Misdiagnosed As Peripheral Vascular Disease

Burning extremity pain with thrombocytosis should prompt JAK2/calreticulin workup before labelling it peripheral vascular disease; triple-negative essential thrombocytosis still carries real thrombotic risk.

General Medicine · Cureus · 6d