Archive

Epic shifts focus to cybersecurity while AI, interoperability agenda still on track, company says

If your hospital runs Epic, expect tighter security controls and continued AI and interoperability rollouts that will change how you document and share records.

General Medicine · Fierce Healthcare · 23 Sept

Immunovant ends cutaneous lupus program after phase 2 flop

Anti-FcRn therapy failed in cutaneous lupus, so don't expect this class as a steroid-sparing option for refractory skin disease; existing treatments remain the standard.

General Medicine · Fierce Biotech · 23 Sept

STAT+: UnitedHealth, CVS push back on Medicare plan to curb remote patient monitoring

If CMS tightens remote monitoring billing, your RPM revenue and chronic-disease follow-up workflows could change; insurers are lobbying against the curbs.

General Medicine · STAT News — Health Tech · 23 Sept

STAT+: Epic’s mortality model, and Omada’s future products

Epic's mortality algorithm shapes which elderly patients get flagged for goals-of-care talks, so know its limits before trusting its score at the bedside.

General Medicine · STAT News — Health Tech · 22 Sept

The Pivotal Role of Consultant Physicians in the Early Screening, Diagnosis, and Management of Osteopenia and Osteoporosis: An Expert Opinion

Roughly half of Indian adults have osteopenia, so screen opportunistically and treat before the first fragility fracture, not after it.

General Medicine · Cureus · 22 Sept

The Prognostic Value of Baseline Neutrophil-to-Lymphocyte Ratio for Mortality in Idiopathic Pulmonary Fibrosis: A Systematic Review and Meta-Analysis

A cheap, routine CBC-derived NLR may help stratify mortality risk in IPF patients, guiding closer follow-up and earlier transplant referral without extra cost.

General Medicine · Cureus · 22 Sept

Diagnosis-Related Group Payment Systems and Hospital Efficiency, Quality, and Coding Behavior: A Systematic Review and Narrative Synthesis

DRG payment shifts hospitals toward efficiency but can drive upcoding and skimping on care; expect pressure on your documentation and discharge coding.

General Medicine · Cureus · 22 Sept

Sarcopenia in Chronic Obstructive Pulmonary Disease: Prevalence and Association With Disease Severity in an Indian Tertiary Care Cohort

Sarcopenia tracks with COPD severity in Indian patients, so screen muscle mass and strength in your COPD follow-ups, not just spirometry.

General Medicine · Cureus · 22 Sept

Flexible Laryngoscopy in Unexplained Cough: Institutional Outcomes and Community Practice Patterns

Before referring unexplained chronic cough, note that community practice patterns vary widely and laryngoscopy yield in this series may not justify routine early use.

General Medicine · Cureus · 22 Sept

Murine Typhus Masquerading as Thrombotic Thrombocytopenic Purpura in a Patient With Newly Diagnosed HIV

In febrile thrombocytopenia with renal failure, consider murine typhus before labelling TTP; doxycycline is curative and plasma exchange is not.

General Medicine · Cureus · 22 Sept

Tobacco Use Treatment: Synopsis of the 2026 U.S. Department of Veterans Affairs and U.S. Department of Defense Clinical Practice Guideline.

32 recommendations across 10 topic areas. Strong recommendations: motivational interviewing, FDA-approved pharmacotherapies, varenicline over other monotherapy, combination NRT over NRT monotherapy. Bupropion SR beyond 12 weeks was weak.

General Medicine · Annals · 22 Sept

When Steroids Backfire: Tinea Incognito Following Treatment for Presumed Psoriasis

Steroid-treated plaques that worsen or lose their annular edge should prompt a KOH mount before you escalate immunosuppression.

General Medicine · Cureus · 22 Sept

Vitamin D Supplementation in Granulomatous Disease: Why Individualized Assessment May Be Safer Than Universal Thresholds

No new data. Low 25(OH)D can occur with preserved or raised 1,25(OH)2D, so supplementing on 25(OH)D alone may cause hypercalcaemia or hypercalciuria.

General Medicine · Cureus · 22 Sept

Pharmacokinetic, Pharmacodynamic, and Clinical Outcomes of Vancomycin and β-Lactam Antibiotics in Adults With Augmented Renal Clearance: A Systematic Review

Vancomycin troughs were below 10 µg/mL in more than 60% of ARC patients; AUC/MIC above 400 mg·h/L was reached in 82.14% with once-every-eight-hours dosing versus 46.42% with once-every-twelve-hours dosing.

General Medicine · Cureus · 21 Sept

Levamisole-Adulterated Cocaine-Associated Vasculopathy in a 73-Year-Old Woman: Diagnostic Challenges in Primary Care

In cocaine users with retiform purpura and atypical ANCA, suspect levamisole adulterant rather than primary vasculitis — misdiagnosis leads to unnecessary immunosuppression.

General Medicine · Cureus · 21 Sept

Medical groups, city of Columbus sue to challenge final Medicaid work requirements rule

If you see Medicaid patients, work-reporting rules from January could strip coverage unless courts block them, disrupting chronic-disease care.

General Medicine · Fierce Healthcare · 21 Sept

Chronic Complications Following Dengue Infection: A Scoping Review

Dengue is no longer only an acute illness — ask about persistent fatigue, hepatic and neurological symptoms weeks after recovery, especially in endemic states.

General Medicine · Cureus · 21 Sept

Seroprevalence and Temporal Trends of Syphilis Among Blood Donors at Dhiraj Blood Bank in Waghodia, Gujarat, India: A Retrospective Study

111 (1.49%) samples were VDRL-reactive; 45 (40.5%) of these were confirmed by Syphi Microlisa ELISA, giving an overall seroprevalence of 0.60%. Annual rates were 0.85% in 2023, 0.08% in 2024, and 0.90% in 2025.

General Medicine · Cureus · 21 Sept

Rice-Grain Calcifications: A Classic Sign of Muscular Cysticercosis

Radiographs showed numerous rice-grain calcifications parallel to muscle fibers, consistent with known cysticercosis; myalgia was not attributable to these lesions and resolved within one week with paracetamol alone

General Medicine · Cureus · 21 Sept

A consensus-based guideline for personalized bacteriophage therapy.

The guideline provides over 60 recommendations covering core principles, infrastructure, phage preparation and quality control, clinical administration, monitoring, documentation and future research priorities.

General Medicine · Nature Medicine · 21 Sept

WHO flags growing health workforce gap as workers and patients age

A quarter of doctors retire within a decade while demand rises, so expect longer waits, heavier rosters and pressure to task-shift to nurses and community health workers.

General Medicine · ETHealthworld · 20 Sept

Microbiological Profile of Pathogens Among Patients at a Tertiary Care Hospital in Mumbai, India

Gram-negatives were 1,627 (78.4%); E. coli 543 (26.2%), Klebsiella 519 (25.0%), Pseudomonas 328 (15.8%). MDROs 597 (28.8%), ESBL 369 (17.8%), MRSA 102 (4.9% of isolates; 77.3% of S. aureus).

General Medicine · Cureus · 19 Sept

Etanercept-Induced Cutaneous Necrotizing Vasculitis in a Patient With Rheumatoid Arthritis: A Case Report and Literature Review

After approximately 33 months of etanercept, bilateral petechial and purpuric lower-limb lesions appeared; biopsy showed fibrinoid necrosis of dermal vessels. Etanercept was stopped and lesions resolved completely within approximately 20 days.

General Medicine · Cureus · 19 Sept

Beyond Antibiotics: Bacteriophage Therapy Against Multidrug-Resistant Pathogens in the Era of Antimicrobial Resistance

Up to 80% of chronic infections involve biofilms that shield bacteria from antibiotics; phages can penetrate and disperse these structures and can resensitise resistant bacteria to previously ineffective drugs

General Medicine · Cureus · 19 Sept

Post-acne Erythema: A Systematic Review of Randomized Controlled Trials on the Comparative Efficacy and Safety of Interventions Across Clinical, Instrumental, and Patient-Reported Outcomes

No intervention has proven standard for post-acne erythema; this review maps which randomized options actually reduce redness so you can counsel patients realistically.

General Medicine · Cureus · 18 Sept

Clotting Beyond Boundaries: Extensive Iliocaval Thrombosis Revealing Homozygous Factor V Leiden Mutation in a Young Adult Following Prolonged Air Travel

In a young patient with extensive thrombosis after long-haul travel, test for inherited thrombophilia such as homozygous factor V Leiden, not just provoked VTE.

General Medicine · Cureus · 18 Sept

FDA clears Aptitude’s latest Metrix molecular dx to test for COVID

A faster, more sensitive COVID test could improve turnaround and detection in acute respiratory presentations, though Indian labs will need to validate availability and cost.

General Medicine · Fierce Biotech · 18 Sept

STAT+: A geriatrician explains why AI for older adults deserves careful scrutiny

Before trusting AI triage or risk scores in elderly patients, know that frailty, atypical presentation and multimorbidity can make model outputs misleading.

General Medicine · STAT News — Health Tech · 18 Sept

Procalcitonin-Guided Antimicrobial Therapy: Current Evidence for Clinical Decision-Making and Practical Limitations

PCT-guided therapy reduces antibiotic exposure without worsening major clinical outcomes when used to guide discontinuation; its role in guiding antibiotic initiation remains limited, particularly in sepsis.

General Medicine · Cureus · 18 Sept

Epidemiology of Kyasanur forest disease in India, 2000-2025: a systematic review and meta-analysis.

KFD has spread beyond Karnataka; know the pooled positivity and case-fatality so you suspect it in febrile patients with tick exposure in new districts.

General Medicine · Lancet regional health. Southeast Asia · 18 Sept

Cervical Scrofula Revealing Miliary Tuberculosis and Previously Undiagnosed Advanced HIV: A Case Report

CD4 count 174 cells/mm³, HIV-1 RNA 956,000 copies/mL, positive QuantiFERON-TB Gold, BAL MTB PCR positive with rifampin resistance not detected.

General Medicine · Cureus · 18 Sept

Beyond Pneumonia: A Case of Steroid-Responsive Pulmonary Eosinophilia With Atypical p-ANCA Positivity

When opacities persist on antibiotics, consider eosinophilic lung disease and trial steroids rather than escalating antimicrobials.

General Medicine · Cureus · 17 Sept

Improving Arterial Blood Gas Sampling Practice in the Emergency Department: A Two-Cycle Clinical Audit

Using venous gases to screen COPD exacerbations before arterial puncture can cut a painful, repeated invasive procedure in your emergency patients.

General Medicine · Cureus · 17 Sept

Renal-Limited Thrombotic Microangiopathy Presenting as Acute on Chronic Kidney Failure in the Absence of Schistocytosis

Peripheral smear, autoimmune serologies and skin biopsy were unrevealing; only kidney biopsy showed TMA. She progressed to stage 5 CKD requiring peritoneal dialysis.

General Medicine · Cureus · 17 Sept

Kennedy appoints 8 new US Preventive Services Task Force members

USPSTF grades drive US screening and preventive coverage, so a reconstituted panel may shift recommendations Indian clinicians often follow.

General Medicine · Fierce Healthcare · 17 Sept

De-escalating Therapy in Obstructive Sleep Apnoea After Glucagon-Like Peptide-1 Receptor Agonist-Induced Weight Loss: A Narrative Review

Patients losing weight on GLP-1s may no longer need CPAP, so plan repeat sleep studies and structured de-escalation rather than leaving them on fixed therapy.

General Medicine · Cureus · 17 Sept

Hospitals push back as FDA flags high markups on hospital consumables

Fixed markups on consumables could change what your hospital charges for devices and supplies, so watch how this pricing framework is finalised.

General Medicine · ETHealthworld · 17 Sept

India had largest number of people exposed to 30 days of risky heat from Jun-Aug: Analysis

Expect more heat exhaustion, dehydration and cardiac events this summer; counsel at-risk patients on hydration, timing of outdoor work and medication adjustments.

General Medicine · ETHealthworld · 17 Sept

Chimeric Antigen Receptor T-cell (CAR-T) Therapy in Autoimmune Diseases: A Narrative Review

CAR-T is moving beyond oncology into refractory SLE, systemic sclerosis and vasculitis, so expect referrals for cell therapy in patients who have failed standard immunosuppression.

General Medicine · Cureus · 17 Sept

Sentara Health pilots GW RhythmX's AI precision care platform to support emerging primary care models

If AI risk stratification at the point of primary care proves out, it could change how chronic disease is triaged before specialists ever see the patient.

General Medicine · Fierce Healthcare · 17 Sept