Archive

Characterization and Antimicrobial Susceptibility Patterns of Clinically Significant Non-fermenting Gram-Negative Bacilli Isolated From Clinical Specimens

Pseudomonas aeruginosa 61 (48.03%), Acinetobacter baumannii 53 (41.73%), Stenotrophomonas maltophilia 13 (10.24%). A. baumannii and P. aeruginosa were highly carbapenem-resistant; S. maltophilia remained susceptible to antibiotics tested.

General Medicine · Cureus · 10 Sept

Front-of-pack labels: Food Inc bats for per-serving benchmark in SC, not FSSAI’s ‘per 100 gm’ plan

Per-serving labels understate salt, sugar and fat in foods patients eat in larger amounts, so the benchmark chosen decides how useful your dietary counselling is.

General Medicine · ETHealthworld · 10 Sept

Outbreak of Severe Methemoglobinemia during Maritime Migration.

Median methemoglobin 44.6% (IQR 32.0–55.7); 43% had levels ≥50%. Methylene blue used in 90%. Hemolytic anemia in 38 patients; 2 died. N-methylaniline or metabolites found in 37 of 39 tested patients (95%).

General Medicine · NEJM · 10 Sept

Phenomic profiles and disease patterns of 1.9 million participants from Our Future Health.

Self-reported depression and anxiety prevalence exceeded national estimates; concordance with UK Biobank was r=0.78 for disease prevalence and r=0.80 for clinical correlates. Lung cancer rates were lower than national data.

General Medicine · Nature Medicine · 10 Sept

Rheumatoid Arthritis in Adults: A Review.

About 40% of newly diagnosed patients achieve CDAI remission within 6 months on first-line DMARDs; adding biological DMARDs or JAK inhibitors increases remission or low disease activity to approximately 80%.

General Medicine · JAMA · 10 Sept

Advances in the diagnosis and management of skin and soft tissue infections.

No primary outcome data. Non-purulent SSTI is typically streptococcal; purulent SSTI is typically Staphylococcus aureus. Laboratory testing is of limited use in most patients.

General Medicine · BMJ · 10 Sept

Computable longitudinal patient journeys from structured and unstructured EHR data.

Physician adjudication confirmed high accuracy against a blinded expert reference standard, with high expert physician inter-reviewer agreement. The framework identified large numbers of patients initiating GLP-1 RAs and modelled longitudinal changes in weight and HbA1c.

General Medicine · Nature Medicine · 10 Sept

Exploring high priority potentially inappropriate prescribing cascades in older adults: population level retrospective cohort study.

24 cascades (37%) met all three criteria. Highest incidence: iron supplement to laxative 11.9% (95% CI 11.7% to 12.1%), statin to pain reliever 10.9% (10.7% to 11%).

General Medicine · BMJ · 10 Sept

A bispecific CD3×CD19 antibody for systemic lupus erythematosus: a phase 1 trial.

No treatment-related serious adverse events, deaths, or grade ≥3 CRS/neurotoxicity; CRS mostly grade 1 (91.6%, 11/12). Exploratory: 80% (8/10) achieved LLDAS and 60% (6/10) DORIS at 12 months.

General Medicine · Nature Medicine · 10 Sept

STAT+: Can AI fix the emergency room?

AI won't solve ER overcrowding or staffing shortages; focus on systemic fixes, not tech hype.

General Medicine · STAT News — Health Tech · 9 Sept

Increases in healthcare spending the largest driver behind premium growth: Yale study

Understanding that spending—not insurer profit—drives premiums helps you advocate for cost-effective care and explain rising patient costs.

General Medicine · Fierce Healthcare · 9 Sept

With elderly population set to double by 2050, govt looks to step up healthcare, caregiving services

Expect more geriatric-focused services and referrals; plan for rising multimorbidity and caregiver support in your practice.

General Medicine · ETHealthworld · 9 Sept

Lenacapavir-Based Salvage Therapy in Heavily Treatment-Experienced Multidrug-Resistant HIV-1: A Case Report From the United Arab Emirates

After virologic rebound in 2023 and failure of salvage regimens, lenacapavir with BIC/FTC/TAF in 2024 produced a rapid undetectable viral load, with suppression maintained to date.

General Medicine · Cureus · 9 Sept

Distribution of gyrA, rrs, and eis Gene Mutations Associated With Second-Line Drug Resistance Among Multidrug-Resistant Mycobacterium tuberculosis Isolates

FQ resistance in 30 (35.3%) isolates, SLID resistance in 7 (8.2%). Commonest FQ mutation gyrA D94G (53.3%), then A90V (20.0%), D94N/Y (16.7%). rrs A1401G in 28.6% and G1484T in 14.3% of SLID-resistant isolates; no eis mutations.

General Medicine · Cureus · 9 Sept

Differences Between Oncological and Non-oncological Patients Referred to an In-Hospital Palliative Care Support Team: A Retrospective Cohort Study in Northern Portugal

In-hospital mortality was 48.9% (44/90) in non-oncological versus 19.8% (21/106) in oncological patients; transfer to a specialist palliative care unit was 16.7% (15/90) versus 42.5% (45/106).

General Medicine · Cureus · 9 Sept

STAT+: Can AI fix health care? In the chaos of emergency rooms, the technology comes up short

AI tools underdeliver in real ED chaos; don't rely on them for critical triage decisions yet.

General Medicine · STAT News — Health Tech · 9 Sept

Beeline flies into phase 3 as oral lupus drug soars past placebo

An oral option for lupus could reduce injection burden; watch for phase 3 efficacy and safety data before changing practice.

General Medicine · Fierce Biotech · 9 Sept

ICMR-NIV study detects insecticide resistance in dengue vector mosquitoes in parts of Pune

If you manage dengue cases, expect control failures in Pune; consider alternative vector control and patient counselling on prevention.

General Medicine · ETHealthworld · 9 Sept

Forus secures $150M series C to grow AI-powered medication access platform

If adopted locally, this could streamline prior authorisations and medication access workflows across specialties, reducing delays for patients starting treatment.

General Medicine · Fierce Healthcare · 8 Sept

AZ's R&D chief Barr touts internal 'science success story' after IL-33 antibody's stellar showing in COPD

FDA priority review for itepekimab could give COPD patients a new biologic option beyond standard inhalers, potentially reducing exacerbations in this hard-to-treat population.

General Medicine · Fierce Biotech · 8 Sept

Wildfire smoke and health: current evidence, mechanisms, and future challenges.

No primary outcome or effect estimate reported. Authors state key gaps persist: long-term health effects, interactions with pre-existing conditions, and health disparities.

General Medicine · Lancet · 8 Sept

Effectiveness of a trivalent inactivated split-virion influenza vaccine (Tri Fluvac) in Thailand: a phase IV test-negative case-control study.

Adjusted vaccine effectiveness against medically attended outpatient laboratory-confirmed influenza was 73.1% (95% CI 66.3-78.5). Influenza was confirmed in 703 (14%) of 4975 participants.

General Medicine · Lancet regional health. Southeast Asia · 8 Sept

Effect of Delayed Presentation on the Prognosis of Snakebite Victims at a Tertiary Care Hospital: The Golden Hour Matters

Mortality was 75% (3/4) in the 18-24-hour group versus 7.1% (1/14) in the zero-to-six-hour group. Recovery was highest in the zero-to-six-hour group at 71.4%.

General Medicine · Cureus · 8 Sept

Imaging Pulmonary Embolism in the Era of Subsegmental Clots: What the Internist Needs to Know About Overdiagnosis, Anticoagulation, and Follow-Up

Short-term recurrence rates in SSPE are low and do not differ significantly from proximal PE. No randomized controlled trial data guide anticoagulation; selected low-risk patients may be safely observed.

General Medicine · Cureus · 7 Sept

When an Extra X Means Extra Risk: Venous Thromboembolism in Klinefelter Syndrome

Massive bilateral pulmonary embolism with concurrent DVT occurred despite normal hematocrit (48.8% at admission, normal over 13 months), negative thrombophilia panel, implicating KS-intrinsic hypercoagulability.

General Medicine · Cureus · 7 Sept

Acupuncture-Induced Pneumothorax Following Thoracic Acupuncture in a Patient With Ehlers-Danlos Syndrome: A Case Report

Left apical pneumothorax (2.8 cm) developed; aspiration removed 450 mL air, but repeat imaging showed minimal reduction; resolved spontaneously within 24 hours.

General Medicine · Cureus · 7 Sept

IIT Madras patents polymer tech that disintegrates bacteria on surfaces without harming human cells

Offers a non-antibiotic surface coating to curb hospital-acquired infections and superbug spread, potentially reducing reliance on conventional antimicrobials.

General Medicine · ETHealthworld · 7 Sept

FSSAI to tighten scrutiny, weighs central ban on non-dairy paneer

A central ban would curb adulterated analogue paneer in your patients' diets, reducing risks from undeclared fats and additives.

General Medicine · ETHealthworld · 6 Sept

Delhi HC backs NMC: Fragmented foreign medical degrees not enough for FMGE eligibility

If you supervise or train FMGE aspirants, this ruling tightens verification—fragmented foreign training won't qualify, affecting recruitment and credential checks.

General Medicine · ETHealthworld · 5 Sept

Pre-exposure prophylaxis as a complementary vaccination strategy to reduce rabies in Kerala, India: a cost-effectiveness modelling study.

Current practice projected 431 rabies deaths (95% PI 353-523) costing US$50.3 million; PrEP added US$10.5-36.5 million and prevented only ten additional deaths; probability of being optimal ≤12%.

General Medicine · Lancet regional health. Southeast Asia · 5 Sept

Medulance Raises ₹24 Cr To Expand Emergency Response Network

Expands ambulance availability and response times for your patients in emergencies, potentially improving critical care access across cities.

General Medicine · Inc42 · 4 Sept

STAT+: OpenEvidence launches new family of AI models

If these models improve clinical evidence retrieval, you may get faster, more accurate answers at the point of care—worth trialing in your workflow.

General Medicine · STAT News — Health Tech · 3 Sept

Leading medical groups release flu, COVID vaccine recommendations as CDC guidance lags

With CDC silent, these recommendations give you a clear vaccination schedule for flu and COVID to follow this season.

General Medicine · Fierce Healthcare · 2 Sept

COVID-19 Vaccine Effectiveness and Safety for the 2026-2027 Respiratory Season.

Vaccine effectiveness against hospitalization: 53.0% (95% CI, 37.0%-65.0%) in ≥65 years (2025-26) and 54.0% (95% CI, 1.0%-78.0%) in 18-64 years (2024-25). Maternal vaccination reduced infant hospital contacts by 50.0%-54.0%.

General Medicine · JAMA · 2 Sept

ChatGPT for Healthcare unveils new integrations with Epic, public health data sources

If you use Epic, ChatGPT may soon sit inside your workflow, pulling patient data and public health context—potentially saving clicks but demanding vigilance on accuracy.

General Medicine · Fierce Healthcare · 1 Sept

Surge in H1N1 cases isn’t unusual, vigilance remains key: Doctors

Reassures you that current H1N1 rise is seasonal, not a new strain—so continue standard testing and antiviral protocols without alarm.

General Medicine · ETHealthworld · 1 Sept

UnitedHealthcare to nix prior auth on 1,700 services on Oct. 1

Fewer prior auths mean faster approvals for your patients' common procedures, but verify which services qualify before assuming coverage changes.

General Medicine · Fierce Healthcare · 1 Sept

Nourish embeds generative AI assistant into patient app for 24/7 support

Gives your patients between-visit meal planning, lab insights, and prep support—could reduce phone calls and improve adherence, but evidence is thin.

General Medicine · Fierce Healthcare · 1 Sept

Drug-resistant infections kill more, cost more: ICMR study

For clinicians, this quantifies the mortality and cost burden of resistant Gram-negative infections, urging early culture-guided therapy and stewardship.

General Medicine · ETHealthworld · 1 Sept

GSK catches phase 3 fever after mRNA flu vaccine beats standard shots

If phase 3 confirms, mRNA flu shots could offer better protection than current vaccines, changing your seasonal flu recommendations.

General Medicine · Fierce Biotech · 1 Sept