Archive

Does Reconstructive Surgery Improve Psychological Recovery After Burn Injury?

Reconstruction may restore function without resolving depression or PTSD, so screen burn survivors psychologically rather than assuming surgery alone fixes recovery.

General Surgery · Cureus · 29 Sept

H1N1 dominates flu strains in India, accounts for 3 out of 4 cases: WHO

With H1N1 causing three of four flu cases, test and treat influenza early in febrile patients rather than presuming dengue or COVID.

General Medicine · ETHealthworld · 29 Sept

Single-Ball Versus Double-Ball Flexor Carpi Radialis Interposition Arthroplasty Following Trapeziectomy: A Retrospective Radiological Study

Radiological comparison of single- versus double-ball FCR interposition after trapeziectomy helps you choose the technique that better preserves thumb height and joint space.

Orthopaedics · Cureus · 29 Sept

Combined Vitamin B12 and Folate Deficiency Presenting As Pseudo-Thrombotic Microangiopathy With a Disseminated Intravascular Coagulation (DIC)-Like Coagulation Profile: A Case Report

Haematologic and coagulation parameters improved within one week of starting vitamin B12 replacement; folic acid was started only after that first week

General Medicine · Cureus · 29 Sept

Associations Among Glycemic Variability, Hypomagnesemia, Thyroid Function, and Albuminuria in Patients With Type 2 Diabetes Mellitus: A Cross-Sectional Study

Beyond HbA1c, visit-to-visit glucose swings and low magnesium tracked with albuminuria in T2DM, suggesting both as cheap add-on risk markers in Indian clinics.

Endocrinology · Cureus · 29 Sept

Inflammatory Myofibroblastic Tumor of the Bladder Following Intravesical Bacillus Calmette-Guérin Therapy: A Case Report

After intravesical BCG, a new bladder mass may be inflammatory myofibroblastic tumour, not recurrence — consider it before committing to radical cystectomy.

Urology · Cureus · 29 Sept

Long-Term Outcome of West Syndrome Treated With Adrenocorticotropic Hormone-Based Therapy in a Tertiary Care Hospital in Bangladesh

Reinforces ACTH as first-line for infantile spasms and quantifies the seizure and developmental trajectory you can counsel families to expect.

Paediatrics · Cureus · 29 Sept

Persistent Apical Akinesis Following Takotsubo Syndrome With Marked Troponin Elevation: A Case Report

Not all takotsubo wall-motion abnormalities resolve; persistent apical akinesis with high troponin can mimic infarction and warrants follow-up imaging before discharge.

Cardiology · Cureus · 29 Sept

Diagnostic and Severity Assessment of Acute Pancreatitis Using Acoustic Radiation Force Impulse Shear Wave Elastography (ARFI-SWE): A Case-Control Study

If pancreatic stiffness on ultrasound tracks severity, you could stratify acute pancreatitis at the bedside without radiation or a CT.

Gastroenterology · Cureus · 29 Sept

Non-alcoholic Fatty Liver Disease/Metabolic Dysfunction-Associated Steatotic Liver Disease and the Risk of Incident Atrial Fibrillation: An Updated Systematic Review and Meta-Analysis of Cohort Studies

Pooled risk ratio for incident AF with NAFLD/MASLD was 1.23 (95% CI 1.12-1.34, p<0.001), with I²=99.4%. In three studies, hepatic fibrosis showed RR 1.19 (95% CI 1.11-1.28).

Gastroenterology · Cureus · 29 Sept

Silent Aortic Disease Can Offer a Narrow Window to Save the Heart’s Own Valve

Aortic root aneurysms stay silent until late; referring earlier keeps patients eligible for valve-sparing David procedures instead of replacement and lifelong anticoagulation.

Cardiology · ETHealthworld · 29 Sept

Post-COVID Gastrointestinal Symptoms and Disorders of Gut-Brain Interaction: A Focus on Persistent Diarrhea

About 1 in 10 long-COVID patients has persistent diarrhea; treat it as a disorder of gut-brain interaction, not as an interchangeable post-viral GI symptom.

Gastroenterology · Cureus · 29 Sept

A Prospective Observational Study of Infantile Dermatoses in Infants Aged 29 Days to 12 Months at a Rural Tertiary Care Center in North India

Eczematous/inflammatory dermatoses were the largest group (n = 93, 46.5%): atopic dermatitis (n = 28, 14%), diaper dermatitis (n = 25, 12.5%), seborrheic dermatitis (n = 22, 11%), irritant contact dermatitis (n = 15, 7.5%).

Paediatrics · Cureus · 29 Sept

Laparoscopic Transabdominal Preperitoneal Repair for a Recurrent Inguinal Hernia After Direct Kugel Procedure: A Case Report

Laparoscopic transabdominal preperitoneal repair was completed, with full coverage of the myopectineal orifice and adequate overlap; no recurrence or complication reported in the abstract.

General Surgery · Cureus · 29 Sept

Diagnostic Accuracy of Rapid Diagnostic Tests Versus Enzyme-Linked Immunosorbent Assay (ELISA) Across Major Infectious Diseases: A Systematic Review and Meta-Analysis

RDTs trade some sensitivity for speed versus ELISA, so know the disease-specific gap before relying on a negative point-of-care result.

General Medicine · Cureus · 29 Sept

Association of the Triglyceride–Glucose Index with Systolic and Diastolic Blood Pressure Among Patients With Type 2 Diabetes Mellitus

A cheap index from routine fasting lipids and glucose may flag T2DM patients heading for hypertension, so you can intensify BP surveillance without extra tests.

Endocrinology · Cureus · 29 Sept

Diagnostic Challenge of Primary Psychiatric Catatonia Versus Seronegative Autoimmune Encephalitis in Pediatrics: A Case Report

Despite negative autoimmune workup, elevated interleukin-2 receptor suggested seronegative autoimmune encephalitis; high-dose lorazepam (18 mg/day), IVIG, corticosteroids, and ECT led to substantial improvement with return of bilingual speech.

Psychiatry · Cureus · 29 Sept

Double-Vessel Involvement: A Case Report of Simultaneous Left Anterior Descending Artery (LAD) and Right Coronary Artery (RCA) Spontaneous Coronary Artery Dissection Causing Acute Coronary Syndrome

Angiography confirmed spontaneous coronary artery dissection in both the left anterior descending artery and right coronary artery, with moderate ischemic cardiomyopathy, an apical clot, and subclavian artery occlusion suggesting vasculitis

Cardiology · Cureus · 29 Sept

Dehydration in Tropical Fevers: Rethinking Fluid and Electrolyte Replacement

Dengue and scrub typhus cause isotonic and hypotonic losses that standard crystalloid protocols may worsen; reassess fluid choice and rate in these fevers.

General Medicine · Cureus · 29 Sept

Atrial Fibrillation in Tribal and Non-tribal Populations: A Comparative Analysis From Eastern India

Tribal AF patients in eastern India may differ in rheumatic vs cardiometabolic drivers and anticoagulation uptake, so check whether your tribal patients are being anticoagulated to the same standard.

Cardiology · Cureus · 29 Sept

Werner helicase inhibitor for advanced microsatellite instability solid tumors: a phase 1 trial.

First-in-class WRN inhibitor shows early activity in MSI-high tumours that have exhausted standard options, though phase 1 dosing and toxicity data are still maturing.

Oncology · Nature Medicine · 29 Sept

Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a double-blind, parallel-group, randomised, placebo-controlled, phase 3 trial.

Triple GIP/GLP-1/glucagon agonism adds another injectable option for patients with obesity and type 2 diabetes who fail current GLP-1 therapy.

Endocrinology · Lancet · 29 Sept

Retatrutide, a Triple Hormone Receptor Agonist, for Treatment of Obesity.

A triple GIP/GLP-1/glucagon agonist given weekly for 80 weeks produced substantial weight loss in adults with obesity without diabetes, adding a third incretin option beyond current dual agonists.

Endocrinology · NEJM · 29 Sept

Phylogeny-agnostic strain-level prediction of phage-host interactions from genomes using machine learning.

Could speed matching of phages to a patient's resistant strain, making phage therapy practical where antibiotic options are exhausted.

General Medicine · Nature microbiology · 29 Sept

Oral small-molecule GLP-1 receptor agonist safiglipron in early type 2 diabetes: a randomized, double-blind, placebo-controlled trial.

An oral GLP-1 agonist taken without fasting or diet rules could offer injection-free glycaemic control for early type 2 diabetes, pending full efficacy and safety data.

Endocrinology · Nature Medicine · 29 Sept

Exercise Therapy and Education for Young Adults With Persistent Knee Problems After Anterior Cruciate Ligament Reconstruction : A Randomized Clinical Trial.

At 4 months KOOS4 improved 14.1 with SUPER versus 9.4 control (adjusted mean difference 4.8, 95% CI 1.4 to 8.2). Global rating of change for pain 73% versus 40%. No cartilage differences.

Orthopaedics · Annals · 29 Sept

FDA Approves First Treatment for MCT8 Deficiency

First approved therapy for this rare X-linked thyroid hormone transport defect; tiratricol lowers peripheral thyrotoxicosis, so paediatricians and endocrinologists can now offer disease-directed treatment rather than supportive care.

Endocrinology · FDA — Press Announcements · 29 Sept

When Morphology Falls Short: ATP1B1::PRKACB Fusion in a Morphologically Atypical Pancreatic Intraductal Oncocytic Neoplasm

Atypical pancreatic intraductal lesions lacking classic oncocytic features can still harbour PRKACB fusions, so molecular testing may be needed when morphology alone is ambiguous.

Gastroenterology · Cureus · 29 Sept

Psoriatic Arthritis Without Cutaneous Manifestations: A Case of Diagnostic Delay, Pathologic Progression, and Psychological Burden

No skin lesions; family history of psoriasis in daughter and grandson prompted PsA diagnosis. DMARD plus escitalopram gave significant pain and mood improvement within one month.

General Medicine · Cureus · 29 Sept

Diagnostic Challenges and Uterus-Conserving Surgical Management Following Systemic Multi-dose Methotrexate for a Left Interstitial Pregnancy

Interstitial ectopic can mimic early intrauterine pregnancy on TVUS; multi-dose methotrexate may fail, so keep laparotomy and cornual resection ready to preserve the uterus.

Obstetrics & Gynaecology · Cureus · 29 Sept

Immunomodulatory Properties of Mesenchymal Stem Cells and Their Extracellular Vesicles: Potential Clinical Applications in Autoimmune Diseases

MSC-derived exosomes may offer cell-free immunomodulation for autoimmune disease, but this is a narrative review — no trial data yet to change your practice.

General Medicine · Cureus · 29 Sept

Multiple Myeloma Presenting as a Pancoast-Like Tumor: A Diagnostic Challenge

An apical lung mass in a smoker is not always Pancoast carcinoma; myeloma can mimic it, so biopsy before committing to lung-cancer treatment.

Oncology · Cureus · 28 Sept

Complete Heart Block in Young Patient With Systemic Lupus Erythematosus: A Case Report

In young SLE patients, screen for conduction disease with baseline ECG even without syncope, since complete heart block can be asymptomatic and need pacing.

Cardiology · Cureus · 28 Sept

Legal Frameworks for Governing Generalist and Agentic Artificial Intelligence in Medical Imaging

Regulators approve fixed single-task imaging AI, but agentic systems that chain models and act on findings fall outside that framework, so accountability for their output is currently unclear.

Radiology · Cureus · 28 Sept

Comparing General Anaesthesia With Spinal Anaesthesia for Holmium Laser Enucleation of Prostate: A Systematic Review and Meta-Analysis

Spinal anaesthesia for HoLEP appears comparable to general anaesthesia, so comorbid BPH patients may avoid airway and systemic risks of GA.

Urology · Cureus · 28 Sept

Beyond Hematuria: An Unexpected Diagnosis of Autosomal Dominant Polycystic Kidney Disease in a Young Adult Without a Family History

In a young adult with hematuria, don't stop at UTI or stones—absence of family history does not exclude ADPKD, and imaging plus renal function changes management.

General Medicine · Cureus · 28 Sept

Non-Hormonal Treatments for Vasomotor Symptoms of Menopause: An Up-to-Date Review

No trial data or effect sizes reported; non-hormonal options show variable effects and potency, with fewer side effects and contraindications than hormonal therapy

Obstetrics & Gynaecology · Cureus · 28 Sept

Fat Emboli Entrapped in the Tricuspid Valve Chordae Following Autologous Fat Grafting: An Echocardiographic-Pathological Correlation

Fat embolism after lipofilling can cause cardiac arrest in healthy young patients; echocardiography showing tricuspid chordae entrapment may aid post-mortem and antemortem diagnosis.

Cardiology · Cureus · 28 Sept

Serum Vascular Endothelial Growth Factor and C-reactive Protein Serve As Biomarkers of Joint Health in Severe Haemophilia A: A Cross-Sectional Study From India

VEGF and CRP may flag haemophilic joint damage in Indian patients on on-demand factor, where imaging and prophylaxis access are limited.

General Medicine · Cureus · 28 Sept

OpenEvidence partners with Anthropic, Penn Medicine to expand physician access to AI across Africa and Asia

If you practise where specialist advice is scarce, this puts an AI second opinion on drug and diagnostic decisions at the point of care.

General Medicine · Fierce Healthcare · 28 Sept