Archive

Implementation of A Randomized Trial of Induction Versus Expectant Management (ARRIVE) in a Community Hospital-Based Obstetric Practice

If your unit adopts 39-week induction for low-risk nulliparas, expect fewer cesareans — but audit your own neonatal outcomes, since community results may differ from the trial.

Obstetrics & Gynaecology · Cureus · 3d

Reducing Short-Acting Beta-2 Agonist (SABA) Overuse in Asthma: A Quality Improvement Project in Primary Care

Patients issued two SABA inhalers fell 62.8% from 94 to 35; patients reporting at least one poor-control symptom fell 51.4% from 37 to 18. In cycle two, 18/23 (78.2%) contacted still reported poor control.

General Medicine · Cureus · 3d

Archive-Recorded Volume Change in Matched Renal Target Lesions: A Secondary Analysis of Public Pediatric Oncology Annotations

Highlights that public pediatric trial archives can support longitudinal lesion-volume tracking only if lesion identity and exam selection are rigorously matched — a caution for anyone mining imaging archives.

Oncology · Cureus · 3d

Streptococcus anginosus Infective Endocarditis Complicated by a Paravalvular Aortic Abscess in a Patient With a Bicuspid Aortic Valve

In bicuspid valve patients, six weeks of vague constitutional symptoms with embolic infarcts warrants echo before abscess forms — S. anginosus endocarditis is rare but destructive.

Cardiology · Cureus · 3d

Association Between Targeted Early EKG Ordering and Emergency Department Length of Stay Among Psychiatric Patients in Southern New Jersey: A Retrospective Study

If early ECG ordering shortens medical clearance, psychiatric patients board less in your ED — but the retrospective design means confirm locally before changing intake order sets.

Psychiatry · Cureus · 3d

Embedding Postoperative Driving Advice Into Electronic Discharge Documentation After Elective Joint Replacement: A Closed-Loop Quality Improvement Project

Standardising driving and insurance advice in the discharge summary closes a medico-legal gap you currently leave to verbal counselling after hip and knee replacement.

Orthopaedics · Cureus · 3d

Endogenous Endophthalmitis Due to Streptococcus agalactiae With a Suspected Urinary Source in a Patient Without Systemic Symptoms at Presentation: A Case Report

In an afebrile elderly diabetic with endophthalmitis, hunt for a silent urinary source of GBS — the eye may be the only sign of invasive infection.

Ophthalmology · Cureus · 3d

Systemic Laboratory Alterations Associated With Heart Failure in Severe Mitral Regurgitation: A Retrospective Observational Study

A post hoc model combining age, sex, C-reactive protein, anemia and eGFR below 60 showed an odds ratio of 5.56 (95% CI 1.94-15.94; P = 0.001) for heart failure; CRP and anemia were not significant after mutual adjustment.

Cardiology · Cureus · 3d

Ischemic Stroke as the Initial Presentation of an Underlying Neuroinfectious Disease

In young or recurrent stroke with atypical imaging, consider neuroinfectious vasculitis — it mimics routine cerebrovascular disease and changes workup and treatment.

Neurology · Cureus · 3d

Pediatric Experience With Ultrasound-Guided Crosswise Approach to Popliteal Sciatic (CAPS) Block for Clubfoot Surgery: A Retrospective Case Series

A supine-position sciatic block means you can anaesthetise a child for clubfoot surgery without turning them prone or resorting to general anaesthesia.

Anaesthesiology · Cureus · 3d

Efficacy and Safety of Ritlecitinib in Severe Alopecia Areata: A Systematic Review

JAK3 inhibition is now a systemic option for totalis/universalis patients you currently have little to offer beyond steroids; know the response and adverse-event profile before prescribing.

General Medicine · Cureus · 3d

Midstream Health nabs $20M series A to help hospitals recover lost margin

If your hospital uses such contract-audit AI, recovered underpayments may fund staffing and equipment — but verify the vendor's cut and data access terms.

Medicine · Fierce Healthcare · 3d

Management of Neuropathic Pain in Patients With Spinal Cord Injuries: A Narrative Review

No trial results or effect sizes are presented. The authors conclude that multimodal pharmaceutical, non-pharmaceutical and interventional strategies appear most effective, but response varies between patients and relief remains difficult.

Neurology · Cureus · 3d

Optimizing Dry Eye Management: An Expert Consensus on the Use of Sodium Hyaluronate at Different Concentrations

Gives you an India-specific Delphi consensus on which sodium hyaluronate concentration to pick at each dry eye stage, replacing ad-hoc lubricant selection.

Ophthalmology · Cureus · 3d

Role of Transurethral Resection of the Prostate (TURP) in Chronic Kidney Disease Patients With Obstructive Uropathy

Before writing off CKD in an elderly man with BPH, remember relief of obstruction may recover renal function — weigh TURP's operative risk against that chance.

Urology · Cureus · 3d

Feasibility of Developing a Music Therapy Program for Radiation Oncology Outpatients at a Large Canadian Cancer Center: A Cross-Sectional Survey

95.0% considered music therapy relevant to radiation oncology patients and 87.5% supported a pilot program, yet only 21.3% saw it as an evidence-based therapy delivered by a trained professional and 5.0% knew the SIO-ASCO guideline.

Oncology · Cureus · 3d

Two-Minute Home Wearable Vital-Sign Monitoring Around Thoracic Surgery: A Single-Participant Technical Feasibility and Data Quality Analysis

Of 25,200 planned two-minute epochs, 22,226 were timestamped (88.2%). Valid data yield was 96.7% for HR and the BP pair but 46.7% for SpO₂; all four vital signs concurrent in 46.6%. Zero-value outputs drove most invalid SpO₂ readings.

Anaesthesiology · Cureus · 3d

Disseminated Bullous Impetigo in an Immunocompetent Young Adult Following Travel to Costa Rica

Consider disseminated staphylococcal bullous impetigo in healthy adults with widespread bullae after minor abrasions, not just children, so you culture and treat rather than mislabel it.

General Medicine · Cureus · 3d

Weight-loss injections are not PMOS cure; experts caution against self-medication

GLP-1s alone won't treat PCOS; individualise by metabolic and fertility goals and warn patients off self-sourcing these drugs for weight loss.

Endocrinology · ETHealthworld · 3d

A Rare Complication of Molar Pregnancy: Uterine Perforation With Ileal Incarceration Following Suction Curettage

Hours after an apparently uncomplicated suction D&C, CT showed fundal perforation with small bowel herniation; laparotomy found 10 cm of ileum inside the uterine cavity, reduced without resection. β-hCG normalised within three months.

Obstetrics & Gynaecology · Cureus · 3d

Bilateral Umbilical Artery Avulsion During Robot-Assisted Pelvic Lymphadenectomy for Endometrial Cancer: A Case Report Emphasizing Safe Hemostatic Management

Absent haptic feedback means you can avulse vessels without feeling it; know that umbilical artery injury is possible in robotic pelvic surgery and plan hemostasis that avoids thermal spread.

Obstetrics & Gynaecology · Cureus · 3d

Global, regional and national burden of cervical cancer in 1990-2023 with forecasts to 2050: a Global Burden of Disease study.

887,000 new cases in 2023 despite HPV vaccination and screening means your eligible women still need catch-up vaccination and screening uptake pushed, not assumed.

Obstetrics & Gynaecology · Nature Medicine · 3d

Myeloid-derived TGFβ1 and oncostatin M establish two distinct stromal niches controlling late and hybrid EMT states.

Two myeloid signals, TGFβ1 and oncostatin M, steer tumours into distinct hybrid EMT states — a mechanistic handle on the plasticity that drives therapy resistance.

Oncology · Nature cancer · 3d

Neoadjuvant botensilimab with or without balstilimab in pMMR and dMMR colon cancer: the phase 2 UNICORN trial.

If an Fc-enhanced anti-CTLA-4 antibody shrinks pMMR colon tumours preoperatively, the mismatch-repair barrier to immunotherapy in your resectable patients may not be absolute.

Oncology · Nature Medicine · 3d

TAVR in Patients with Moderate Aortic Stenosis with At-Risk Features.

If TAVR beats surveillance in moderate AS with at-risk features, the watch-and-wait echo-every-1-2-years approach for these patients may shift toward earlier intervention.

Cardiology · NEJM · 3d

Povorcitinib for nonsegmental vitiligo: two randomized, controlled, phase 3 STOP-V trials.

An oral JAK1 inhibitor with 52-week phase 3 data would be the first systemic option for moderate-to-severe vitiligo, a condition you currently manage with topical steroids and off-label use.

General Medicine · Nature Medicine · 3d

Antithrombotic Therapy After Left Atrial Appendage Occlusion: The SIMPLAAFY Randomized Clinical Trial.

If reduced-dose NOACs or aspirin alone match DAPT after LAAC, you can cut bleeding risk in these often frail, elderly patients without sacrificing device safety.

Cardiology · JAMA · 3d

Life-Saving Intervention Through Real-Time Continuous Cardiac Monitoring: A Case of Tachy-Brady Syndrome Detection and Emergency Management

Persistent AF with 3,199 ventricular pauses, the longest 6.6 seconds and unaccompanied by reported symptoms, plus advanced AV conduction disease and no ventricular tachyarrhythmias — consistent with tachy-brady syndrome

Cardiology · Cureus · 3d

Comparative Cost-Effectiveness of Prostate-Specific Membrane Antigen Positron Emission Tomography Agents and Conventional Imaging for Initial Diagnosis of Prostate Cancer in the United States

PSMA PET staging is more sensitive than conventional imaging but costs more; this analysis quantifies whether that trade-off holds for your newly diagnosed patients.

Oncology · Cureus · 4d

Pioglitazone-Mediated Reduction of Ectopic Fat in Metabolic Dysfunction-Associated Steatotic Liver Disease

Pioglitazone shifts fat out of liver and viscera into subcutaneous stores, so it can improve steatosis and insulin resistance in MASLD — but weigh weight gain and fluid retention.

Endocrinology · Cureus · 4d

Athenahealth launches tool to bring patient health records into Anthropic's Claude

Patients will soon query their own records through Claude and arrive with AI-generated interpretations; expect to correct summaries and clarify what the data does and doesn't mean.

General Medicine · Fierce Healthcare · 4d

Artificial Intelligence Versus Human Interpretation in Diagnostic Radiology: A Systematic Review of Diagnostic Accuracy and Operational Efficiency

AI matched or beat human readers on accuracy in most included studies, but reporting was inconsistent — treat vendor accuracy claims as unverified until locally validated on your scanners and population.

Radiology · Cureus · 4d

Current Evidence and Future Directions in the Management of Stage II Gallbladder Cancer

T2 gallbladder cancer is curable but recurs often; this review covers staging quality, radical cholecystectomy standards and risk-adapted adjuvant therapy you can apply to incidentally detected cases.

General Surgery · Cureus · 4d

Comparative Outcomes of Radical Surgery, Conservative Surgery, and Percutaneous Treatment for Active Hepatic Cystic Echinococcosis: A Retrospective Cohort Study

Treatment success was 15/15 (100.0%) with radical surgery, 15/18 (83.3%) with conservative surgery, and 4/8 (50.0%) with PAIR (p = 0.007). Complications were 13.3%, 33.3% and 62.5% respectively (p = 0.038).

General Surgery · Cureus · 4d

Prophylactic Incisional Negative-Pressure Wound Therapy Versus Conventional Dressings in Emergency Colorectal Surgery: A Systematic Review of Randomized Controlled Trials

Weigh whether prophylactic ciNPWT earns its cost over plain dressings in contaminated emergency colorectal wounds, where SSI risk is highest and evidence remains mixed.

General Surgery · Cureus · 4d

Efficacy and Safety of Faropenem in Bangladeshi Adults With Community-Acquired Pneumonia: A Randomized Controlled Trial

Clinical cure at days 10-14 was 98.5% with faropenem versus 95.3% with comparator (risk difference +3.1%, 95% CI -2.8 to +9.1; relative risk 1.03, 95% CI 0.97-1.10). Adverse events 9.2% versus 12.5%; no serious adverse events, no withdrawals.

General Medicine · Cureus · 4d

Reduced Oxycodone Efficacy Associated With Carbamazepine Use in a Patient With Advanced Cholangiocarcinoma

Before escalating opioids in cancer pain, check for enzyme-inducing co-medications like carbamazepine — the interaction, not the disease, may be driving the pain.

Oncology · Cureus · 4d

Adjunctive Cervical Pessary Following Emergency Cerclage for Advanced Cervical Insufficiency With Exposed Fetal Membranes: A Systematic Review of Pregnancy Prolongation and Neonatal Outcomes

Polish cohorts: longer cerclage-to-delivery interval (mean 82.9 vs 52.1 days) and later delivery (34.7 vs 29.7 weeks). Multicentre cohort: fewer deliveries before 28 weeks (3/39 vs 10/35; RR 0.27, 95% CI 0.08-0.90). Indian cohort showed no overall difference.

Obstetrics & Gynaecology · Cureus · 4d

Assam signs Rs 600 crore deal for India's first state-run proton therapy centre

Proton therapy spares surrounding tissue better than photons, so Northeast patients needing skull-base, paediatric or re-irradiation cases may no longer travel abroad or to metros.

Oncology · ETHealthworld · 4d

Efficacy and Safety of Acute Normovolemic Hemodilution in Adult Cardiac Surgery: A Systematic Review and Meta-Analysis of Latest Evidence

If ANH reliably cuts allogeneic transfusion in cardiac cases, it is a cheap, low-risk blood-conservation step you can add to your bypass protocol.

Anaesthesiology · Cureus · 4d