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Archive
1974 items, newest first. Nothing is deleted.
Monday, 21 September 2026
Maternal Bivalent Respiratory Syncytial Virus Prefusion F (RSVpreF) Vaccination in Panama: A Retrospective Follow-Up Study
Any reaction reported by 55.5% (95% CI 48.6%-62.2%), mostly injection-site pain (48.0%); fever 2.5%. Preterm birth 2.0%, low birth weight 2.5%, neonatal jaundice 20.0%.
Obstetrics & Gynaecology · Cureus · 21 Sept
Beyond the Hospital: Spatial Inequality and Structural Divergence in Stroke Mortality Across the United States (2020-2024)
Largest relative increases in medium (+8.4%) and large fringe metros (+7.3%); home deaths surged in 2021 (n=41,423); out-of-hospital Gini=0.5321 versus in-hospital Gini=0.5045.
Neurology · Cureus · 21 Sept
Cell-Type-Specific Transcriptomic Alterations in the Epileptic Prefrontal Cortex and Complementary Neuroimaging Findings in an Independent Cohort
Maps which prefrontal cell types are transcriptionally altered in epilepsy and links them to imaging changes, pointing toward cell-specific targets rather than seizure-focus-only models.
Neurology · Cureus · 21 Sept
FDA Updates Regulations to Advance Innovative Alternatives to Animal Testing
Non-animal safety testing may speed first-in-human entry for new drugs you prescribe or trial, though clinical evidence standards are unchanged.
Medicine · FDA — Press Announcements · 21 Sept
Terminologia Anatomica Compliance in Generative Artificial Intelligence Outputs: A Structured Narrative Review and Terminology-Specific Verification Checklist
Image studies consistently found omissions, invented structures, incorrect relationships and mislabeled anatomy; one citation study found substantial reference hallucination and limited PubMed identifier accuracy
Medicine · Cureus · 21 Sept
Rapid Pain Reduction and Wound Closure Following Treatment With an Amorphous Silica-Based Fiber Wound Matrix in Partial-Thickness Thermal Burns: A Case Report
In this single case, a silica-based fiber matrix relieved refractory 6-10/10 burn pain and achieved closure after standard dressings and analgesia failed.
General Surgery · Cureus · 21 Sept
Thyroid Ectopia in the Euthyroid Patient: A Rare Case Discussion
A midline base-of-tongue mass in a euthyroid patient may be ectopic thyroid, not carcinoma; imaging alone cannot distinguish them, so biopsy before resection.
General Surgery · Cureus · 21 Sept
Evaluation of Pre-analytical Errors in the Histopathology Laboratory at a Tertiary Care Hospital in Kenya
Most histopathology errors happen before the specimen reaches the lab, so tightening collection, labelling and fixation in your own theatre and clinic is where diagnostic quality is won.
Medicine · Cureus · 21 Sept
Chronic Complications Following Dengue Infection: A Scoping Review
Dengue is no longer only an acute illness — ask about persistent fatigue, hepatic and neurological symptoms weeks after recovery, especially in endemic states.
General Medicine · Cureus · 21 Sept
Govt nod for Biovigilance Programme, IPC to monitor adverse events linked to organ transplants
Transplant centres will now report adverse events and reactions to a national IPC programme, so expect new reporting duties and clearer safety signals for your post-transplant patients.
General Surgery · ETHealthworld · 21 Sept
White House plans to put NIH grants under political control: reports
Political review of NIH grants could slow or block funding for trials and studies that shape the evidence behind your clinical decisions.
Medicine · Fierce Healthcare · 21 Sept
Bilateral Staghorn Calculi With Stent Encrustation in a Patient With an Ileal Conduit Requiring Staged Endourological Procedures: A Case Report
Bilateral staghorn calculi, stent encrustation and a conduit calculus were cleared completely using staged percutaneous and transconduit endoscopic techniques, with significant improvement in renal function.
Urology · Cureus · 21 Sept
Bioactivity and Regenerative Potential of Calcium Silicate-Based Endodontic Sealers on Human Periodontal Ligament Stem Cells: A Systematic Review of In Vitro Cellular Mechanisms
Calcium silicate sealers generally maintained or increased metabolic activity while AH Plus showed lower activity; 12 scratch-wound studies showed migration comparable to or greater than controls, and 11 Alizarin Red S studies showed increased mineral deposition.
Medicine · Cureus · 21 Sept
Seroprevalence and Temporal Trends of Syphilis Among Blood Donors at Dhiraj Blood Bank in Waghodia, Gujarat, India: A Retrospective Study
111 (1.49%) samples were VDRL-reactive; 45 (40.5%) of these were confirmed by Syphi Microlisa ELISA, giving an overall seroprevalence of 0.60%. Annual rates were 0.85% in 2023, 0.08% in 2024, and 0.90% in 2025.
General Medicine · Cureus · 21 Sept
Imaging Correlation of Color Doppler Ultrasound, CT Angiography, and MR Angiography Findings in Extracranial Carotid and Vertebral Artery Disease Among Ischemic Stroke Patients: A Prospective Observational Study
Doppler agrees well enough with CTA/MRA for first-line carotid and vertebral stenosis workup, so you can triage stroke patients without immediate advanced angiography.
Neurology · Cureus · 21 Sept
Esophageal Carcinoma Incidence and Survival Analysis: A Population-Based Cancer Registry Study in Central India
Median survival 178.33 days; 1-, 3-, 5-, 10-year OS 31.3%, 19.7%, 17.4%, 14.6%. Median survival 232 days localized vs 68 days distant disease. Chemoradiotherapy HR 0.48, surgery plus chemotherapy HR 0.45.
Oncology · Cureus · 21 Sept
Literature Review of Occult Hepatitis B Infection and Hepatitis B Core Antibody-Positive Blood Donors
Anti-HBc-positive donors with occult HBV can transmit infection where only HBsAg or NAT is used, so know your blood bank's screening algorithm before transfusing.
Gastroenterology · Cureus · 21 Sept
Spontaneous Perigastric Hematoma and Hemoperitoneum Associated With Rivaroxaban Therapy: A Case Report and Review of the Literature
Perigastric hematoma measured 96 mm × 58 mm with hemoperitoneum; hemoglobin fell from 14.8 g/dL to 12.3 g/dL. No active contrast extravasation. Rivaroxaban was stopped and he recovered fully without transfusion or procedure.
Gastroenterology · Cureus · 21 Sept
Prevalence and Pattern of Hemoglobinopathies Among Women of Reproductive Age Attending a Tertiary Care Center in Central Uttar Pradesh: A Prospective Observational Study
Regional prevalence data support offering hemoglobinopathy carrier screening and reproductive counselling to women of reproductive age in Central Uttar Pradesh.
Obstetrics & Gynaecology · Cureus · 21 Sept
Rice-Grain Calcifications: A Classic Sign of Muscular Cysticercosis
Radiographs showed numerous rice-grain calcifications parallel to muscle fibers, consistent with known cysticercosis; myalgia was not attributable to these lesions and resolved within one week with paracetamol alone
General Medicine · Cureus · 21 Sept
Ectopic Ureteral Orifice: An Unusual Cause of Urinary Incontinence in an Adult
CT urography showed a left duplex collecting system with an ectopic ureter draining the upper renal pole into the vagina. Ureterovesical reimplantation (Politano-Leadbetter) gave immediate, complete continence.
Urology · Cureus · 21 Sept
Centre calls for review of Hospital Consumable Prices after Mundhe flags MRP gaps: Sources
If margins on consumables are capped, your hospital's device procurement costs and billing to patients could shift, so watch for pricing changes.
Medicine · ETHealthworld · 21 Sept
Prevalence of Deep Vein Thrombosis in Patients With Cervical Cancer
Baseline and on-treatment DVT screening in cervical cancer patients may catch silent thrombosis before it becomes life-threatening.
Oncology · Cureus · 21 Sept
Analysts ‘extremely bullish’ as Telix beams into Novartis’ territory with $1.6B ITM acquisition
Consolidation of radiopharma supply could affect availability and cost of lutetium-177 therapies you refer patients for, including neuroendocrine and prostate cancer.
Oncology · Fierce Biotech · 21 Sept
Bedside Flexible Cystoscopy-Guided First Suprapubic Catheter Exchange in a High-Risk Patient
Exchange completed without significant bleeding or other complications; direct visualization confirmed intravesical guidewire, catheter tip and balloon positioning, allowing immediate bleeding monitoring
Urology · Cureus · 21 Sept
Basilar Artery Occlusion Associated With Paradoxical Embolism After Traumatic Spinal Cord Injury: A Case Report
CT angiography showed partial distal basilar occlusion; mechanical thrombectomy by direct aspiration achieved complete reperfusion (TICI 3). Echocardiography showed right-to-left shunting with more than 30 microbubbles from the second cardiac cycle.
Neurology · Cureus · 21 Sept
Enhancing Inpatient Echocardiogram Request Appropriateness and Timeliness Using British Society of Echocardiography Guidelines: A Quality Improvement Project
Appropriate requests rose from 82/100 (82%) to 90/100 (90%), an absolute change of 8 percentage points (95% CI −1.7 to +17.8; p=0.153). Completion within 24 hours changed from 77/100 (77%) to 79/100 (79%).
Cardiology · Cureus · 21 Sept
Fornix Reconstruction in Cicatricial Ocular Surface Disease: A Narrative Review of Graft Materials, Surgical Techniques, and Medical Management
Graft choice and adjunctive medical therapy, not surgical technique alone, determine whether fornix depth holds after symblepharon release in severe cicatricial disease.
Ophthalmology · Cureus · 21 Sept
Association of Finerenone Dose and Estimated Glomerular Filtration Rate (eGFR) Slope Changes in Patients With Diabetic Kidney Disease: A Real-World Retrospective Study
Annual eGFR slope improved from -5.20 to +0.27 mL/min/1.73 m²/year (p = 0.0144). The 10 mg/day group improved from -7.11 to +3.35 (p = 0.00041); the 20 mg/day group did not (-3.29 to -2.85, p = 0.865).
Endocrinology · Cureus · 21 Sept
Cue chalks up phase 2 hives win for Xolair challenger
A second oral option for chronic spontaneous urticaria could help patients who fail or cannot tolerate omalizumab injections.
Medicine · Fierce Biotech · 21 Sept
Preventing Penile Retraction After Fournier’s Gangrene: Progressive-Tension Soft-Tissue Fixation for Penile Reconstruction
Progressive-tension fixation during grafting may prevent penile retraction and improve functional outcomes after extensive debridement for Fournier's gangrene.
Urology · Cureus · 21 Sept
Condition-Linked Opioid Prescribed-Medicine Events and Subsequent Emergency Department Use Among Adults With Surgical or Procedural Events: A Longitudinal Medical Expenditure Panel Survey Study
Adjusted mean annual ED visits 0.336 (95% CI 0.275-0.412) with versus 0.345 (95% CI 0.311-0.382) without a linked opioid event; mean ratio 0.975 (95% CI 0.784-1.211).
General Surgery · Cureus · 21 Sept
Understanding and targeting the tumour matrisome.
ECM accumulation tracks with tumour aggressiveness across cancers, so matrix-directed targets may offer a new axis beyond cytotoxic therapy.
Oncology · Nature reviews. Clinical oncology · 21 Sept
A consensus-based guideline for personalized bacteriophage therapy.
The guideline provides over 60 recommendations covering core principles, infrastructure, phage preparation and quality control, clinical administration, monitoring, documentation and future research priorities.
General Medicine · Nature Medicine · 21 Sept
Vaccines for Cancer: A Translational Science Review.
Sipuleucel-T reduced all-cause mortality in metastatic castrate-resistant prostate cancer (32% vs 23%; HR 0.78). Talimogene laherparepvec increased 6-month response in advanced melanoma (16.3% vs 2.1%). mRNA-4157 plus pembrolizumab improved relapse-free survival (76.6% vs 60%).
Oncology · JAMA · 21 Sept
Medicare Advantage Enrollment and Access to Kidney Transplant After the 21st Century Cures Act.
Transplant rates 2.51 vs 4.60 per 1000 person-months (aRR 0.71; 95% CI 0.69-0.72); wait-listing 3.05 vs 4.64 (aRR 0.77; 95% CI 0.75-0.78)
Urology · JAMA · 21 Sept
Severe Suspected Metformin-Associated Lactic Acidosis With Relatively Preserved Serum Creatinine at Presentation: Sequential Intermittent Hemodialysis and Continuous Venovenous Hemodialysis
Lactate was 24.1 mmol/L and peaked at 25.5 mmol/L, total CO2 <5 mmol/L, but creatinine only 1.18 mg/dL. Lactate declined from 25.5 to 16.0 mmol/L before dialysis; normalized after intermittent then continuous hemodialysis.
Endocrinology · Cureus · 21 Sept
Endovascular Thrombectomy in Patients With Cancer and Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
Recanalization 77.1%, sICH 4.5%, mRS ≤2 in 26.8%, 90-day death 39.4%. Versus controls: mRS ≤2 RD -0.170 (95% CI -0.223 to -0.116); mortality RD 0.234 (95% CI 0.168 to 0.300).
Neurology · Cureus · 21 Sept
Antiphospholipid Syndrome as an Under-Recognized Cause of Ischemic Stroke in Older Adults: A Retrospective Case Series
Consider testing antiphospholipid antibodies in stroke patients over 65, not just the young—seven cases here suggest it is missed in older adults.
Neurology · Cureus · 21 Sept