Archive

Racial Disparity in Primary Cesarean Delivery Persists Within Physicians’ Practices: A Multilevel Analysis of Physician Characteristics and Implicit Association Test Results

The Black–non-Black gap in primary cesarean persists within individual physicians' practices, so it is not explained by case-mix alone — audit your own cesarean rates by patient race.

Obstetrics & Gynaecology · Cureus · 6d

ICMR funds study to identify genetic links, potential therapies for autoimmune diseases

Multiplex-family genomic profiling may eventually identify shared immunopathogenic targets, but no diagnostic or therapeutic is available to you yet.

General Medicine · ETHealthworld · 6d

Short-Term Glycemic Response to Tirzepatide According to Prior Incretin Therapy in Patients with Type 2 Diabetes Mellitus

Prior incretin exposure may blunt tirzepatide's HbA1c drop at three months, so set expectations and review timing when switching GLP-1-experienced patients.

Endocrinology · Cureus · 6d

Climate change threatens malaria elimination in the Asia Pacific.

Extreme weather, not just warming, is driving malaria resurgence — Pakistan's post-flood spike shows you should expect outbreak response, not steady seasonal trends.

General Medicine · Nature Medicine · 6d

ANO6-mediated trogocytosis of cancer-associated fibroblasts promotes pancreatic cancer cell growth and immune suppression.

Explains how pancreatic tumours feed themselves through CAF trogocytosis of blood-borne lipids, pointing at ANO6 and stromal lipid handling as targets in a cancer where vessels are scarce.

Oncology · Nature cancer · 6d

BAZ2A-induced epigenetic states in cancer cells fuel palmitate accumulation in the tumor microenvironment driving CAR-T cell exhaustion.

Explains why CD70 CAR-T fails in solid tumours: tumour BAZ2A drives palmitate buildup that exhausts T cells, a targetable resistance axis.

Oncology · Nature cancer · 6d

GALE is a tumor-intrinsic checkpoint of Vγ9Vδ2 T cell-mediated killing.

If GALE loss sensitises tumours to gamma-delta T cells, it becomes a biomarker and target for off-the-shelf cell therapy trials your patients may be offered.

Oncology · Nature cancer · 6d

Selective blockade of microRNA-31-5p-calcitonin receptor interaction reverses established atrial fibrosis and atrial arrhythmia burden.

Targeting miR-31-5p reversed established atrial fibrosis and arrhythmia burden in this model — a first disease-modifying approach for persistent AF, though years from the clinic.

Cardiology · Nature cardiovascular research · 6d

Prion Diseases in Focus: A Review of Diagnosis and Treatment

No curative therapy exists. Protein amplification assays (PMCA, RT-QuIC, tASA) show promising sensitivity and specificity; blood prion protein detection may allow minimally invasive testing. Experimental anti-PrP antibodies and misfolding inhibitors remain unproven.

Neurology · Cureus · 7d

Optimizing Front-Door Sarcopenia Screening on the Acute Medical Unit: A Practical Framework for Frailty Management

No outcome data are reported. The framework combines the validated SARC-F questionnaire with handgrip strength and the chair stand test, to be applied during acute medical assessment.

General Medicine · Cureus · 7d

Quadriceps Strength After Anterior Cruciate Ligament Reconstruction: Mechanisms of Weakness and Evidence-Based Rehabilitation Strategies

Quadriceps weakness after ACL reconstruction is not just atrophy — neural and surgical factors drive it, so target neuromuscular re-education, not only strengthening, in rehab protocols.

Orthopaedics · Cureus · 7d

Endoscopic Retrograde Appendicitis Therapy: A Narrative Review of Current Evidence and Challenges for European Implementation

ERAT preserves the appendix in uncomplicated appendicitis, but this review flags selection criteria and training gaps you'd need settled before offering it over laparoscopic appendicectomy.

General Surgery · Cureus · 7d

Association Between Vitamin A Deficiency and Pneumonia Severity in Hospitalized Children Aged Six Months to Five Years

If admission retinol tracks pneumonia severity in under-fives, it may flag children needing closer monitoring — though infection itself lowers retinol, so causality stays unclear.

Paediatrics · Cureus · 7d

STAT+: The EPIC investigation, and a Teladoc surprise

EHR and telehealth vendors are under scrutiny while AI payment models firm up — the tools you document and consult in are being renegotiated.

Medicine · STAT News — Health Tech · 7d

Effects of Micro-osteoperforation Using a Lance Drill on the Rate of Tooth Movement During Lower Arch En-Masse Retraction in Class I Malocclusion With Bidental Proclination: A Comparative Study

If MOP reliably shortens en-masse retraction time, you can offer patients less time in fixed appliances and fewer caries and root-resorption risks.

Orthopaedics · Cureus · 7d

Comparison of Opioid Utilization With Different Perioperative Pain Protocols After Scheduled Cesarean Delivery

Adding pre-op gabapentin-acetaminophen or liposomal bupivacaine wound infiltration reduced opioid consumption after scheduled cesarean delivery, giving you opioid-sparing alternatives to neuraxial morphine alone.

Obstetrics & Gynaecology · Cureus · 7d

Role of Family Medicine in Acute Diabetic Emergencies and Related Healthcare Utilization: A Systematic Review

Most studies reported fewer acute glycemic events and reductions in diabetes-related or avoidable hospitalisation and emergency care use, but findings were inconsistent; no study reported diabetic ketoacidosis or hyperosmolar hyperglycemic state as individual endpoints

General Medicine · Cureus · 7d

The Learning Curve: Integrating Robotic Appendectomy Into Surgical Residency

No primary data. The authors argue appendectomy's limited scope and surgeon familiarity may let junior residents build console, visualisation, instrument and dissection skills, contingent on case selection, supervision, resources and a structured programme.

General Surgery · Cureus · 7d

Sacubitril/Valsartan Versus Angiotensin-Converting Enzyme Inhibitor or Angiotensin Receptor Blocker Therapy: Rehospitalization Outcomes in a Predominantly Hispanic Population With Heart Failure

Adds real-world rehospitalization data for sacubitril/valsartan in a Hispanic HFrEF cohort, supporting its use where trial populations under-represented this group.

Cardiology · Cureus · 7d

Mobility-Related Disability, Body Mass Index, and Cardiometabolic Disease Among Adults in Puducherry, India: A Cross-Sectional Mediation Analysis

In Puducherry adults, BMI partly mediates the link between mobility disability and hypertension/diabetes — so weight management in disabled patients is cardiometabolic prevention, not just rehab.

General Medicine · Cureus · 7d

Multiple Causes of Death Associated With Stroke in Young Adults Aged 20-49 Years in Brazil: A Population-Based Time-Series Analysis From 2015 to 2024

Young adults dying of stroke often carry coexisting conditions that single-cause coding hides; reviewing the full chain may change how you work up a 30-year-old.

Neurology · Cureus · 7d

Docterz raises Rs 5 Cr from Vineeta Singh, Avnish Anand and 20 doctor-investors

A clinic-management platform whose own doctor users put in 60% of the round — signals clinicians are paying for practice software, though no clinical outcome data is involved.

Medicine · Entrackr · 7d

The Confidence Trap: What a New Survey Reveals About AI and Health Decisions

Patients are already using general-purpose chatbots to decide whether to see you at all, so ask what they were told before dismissing their self-triage.

General Medicine · Fierce Healthcare · 7d

NYU Langone brings OpenEvidence’s clinical AI into the EHR systemwide

An AI answer engine embedded in the EHR at a major academic centre signals where point-of-care evidence retrieval is heading; expect similar tools in your hospital's workflow.

General Medicine · Fierce Healthcare · 7d

The 1-2-3 Rule: When to “Consider” Glaucoma Surgery and Discuss It With Patients

Three prompts trigger surgical discussion: IOP >12 mmHg in progressive advanced glaucoma (mean deviation ≤ −10 dB or central 10° defects), IOP >20 mmHg despite topical treatment in perimetric glaucoma, or ≥3 bottles of IOP-lowering drops; oral acetazolamide is an independent prompt.

Ophthalmology · Cureus · 7d

Global Burden and Elimination Progress of Viral Hepatitis B and C Toward the 2030 WHO Targets: A Structured Review of Epidemiology, Inequities, and Service Delivery Gaps

Age-standardised infection rates declined over recent decades, consistent with vaccination and treatment, but population growth, ageing and pre-vaccination infections kept absolute burden high; most countries are not on course for elimination targets

Gastroenterology · Cureus · 7d

Kennedy's HHS relaxes enforcement on 6 popular wellness peptides

Patients may now ask you about compounded peptides like BPC-157 with no approved safety data; know the regulatory shift before advising them.

General Medicine · Fierce Healthcare · 7d

Comparative Cytomorphologic Performance of Rehydrated Air-Dried and Conventional Papanicolaou Staining in Cervical Smears in a Prospective Paired Study

If air-dried rehydration holds up, your peripheral camps and high-volume labs can drop the race to fix smears in alcohol without losing epithelial detail.

Obstetrics & Gynaecology · Cureus · 7d

Efficacy and Safety of DoceAqualip in a Patient With Metastatic Triple-Negative Breast Cancer Beyond 40 Cycles: A Case Report

A single case of a docetaxel formulation tolerated past 40 cycles in metastatic TNBC is hypothesis-generating only; it does not yet justify changing your regimen or supportive-care plan.

Oncology · Cureus · 7d

Slit-Like Ventricles in Diffuse Cerebral Edema After Cardiac Arrest: A Case Report

Slit-like ventricles on post-arrest CT can reflect diffuse edema rather than normal anatomy, so read them alongside parenchymal loss before prognosticating to families.

Neurology · Cureus · 7d

Clinical Periodontal Outcomes Following Deep Margin Elevation in Posterior Teeth: A Systematic Review and Meta-Analysis

Supports DME as a conservative alternative to crown lengthening for deep subgingival margins, but watch periodontal response when margins encroach on supracrestal attachment.

General Surgery · Cureus · 7d

'Ebola is like Covid pandemic': African CDC chief says no country in the world is safe now

Ebola's early symptoms mimic common febrile illness, so take a full travel and contact history in any fever case — importation risk is not zero anywhere.

General Medicine · ETHealthworld · 7d

Fulminant Emphysematous Hepatic Abscesses Due to Clostridium perfringens With Massive Intravascular Hemolysis: A Case Report

Gas-forming C. perfringens liver abscess can kill within hours; recognise the triad of epigastric pain, haemolysis and rapid deterioration to trigger early surgery and antibiotics.

Gastroenterology · Cureus · 7d

Lactate Kinetics and Procalcitonin Clearance as Predictors of 28-Day Mortality in Patients With Sepsis Admitted to a Medical Intensive Care Unit: A Prospective Observational Study

21% died by day 28. Admission lactate was 8.6 mmol/L (IQR 6.4-12.4) in nonsurvivors versus 3.7 mmol/L (IQR 2.6-4.4) in survivors; PCT clearance AUC 1.000 (95% CI 0.964-1.000) at cutoff ≤38.65%.

General Medicine · Cureus · 7d

Acute Onset Seropositive Rheumatoid Arthritis-Associated Interstitial Lung Disease in the Absence of Articular Symptoms: An Atypical Presentation

Seropositive ILD can present acutely with dyspnea and chest pain mimicking PE before any joint symptoms, so consider RA serology in unexplained acute interstitial patterns.

General Medicine · Cureus · 7d

Return-to-Play After Turf Toe Injuries in Elite American Football Players: A Systematic Review and Clinical Guide

Grade 3 first-MTP capsuloligamentous tears need stability- and sesamoid-based decisions, not blanket conservative care; this guide maps when surgery shortens return to play.

Orthopaedics · Cureus · 7d

HUL backs FSSAI labelling norms for food products high in fat, salt and sugar

Front-of-pack warning labels would let you point patients with diabetes, hypertension or obesity to specific packaged foods to avoid, rather than generic diet advice.

General Medicine · ETHealthworld · 7d

An agentic AI system enhances clinical detection of immune-related adverse events in a multi-phase validation study.

Up to 40% of checkpoint-inhibitor patients develop irAEs that chart review misses; an AI-plus-human workflow could catch them earlier, though you still verify every flag.

Oncology · Nature cancer · 7d

Irritable bowel syndrome and related disorders of gut-brain interaction.

Roughly one in five of your patients has an IBS-spectrum disorder; framing symptoms as gut-brain interaction supports explanation, dietary and neuromodulator strategies over repeated negative workups.

Gastroenterology · Lancet · 7d

Performance of 0/1 h versus 0/3 h pathways in patients with suspected myocardial infarction: a systematic review and individual participant data meta-analysis of randomised controlled trials.

The 0/1 h pathway discharges more suspected-MI patients safely and faster than 0/3 h, so you can shorten ED stays without missing events.

Cardiology · Lancet · 7d